BACKGROUND Heart rate recovery after exercise is an independent prognostic indicator for cardiovascular and all-cause mortality. The purpose of this study was to clarify the clinical determinants of heart rate recovery. METHODS AND RESULTS We examined 114 consecutive male patients who underwent exercise myocardial perfusion single-photon emission computed tomography and echocardiography for t...

backgroundasthma is the most chronic inflammatory disorder of the airways in children and asthmatic patients can experience cardiac dysfunction, pulmonary hypertension and finally cor pulmonale later in life. we aimed to investigate right ventricular (rv) functions in asthmatic children by conventional and tissue doppler echocardiography (tde).materials and methods pulmonary function tests, con...

BACKGROUND Patients with type 2 diabetes mellitus and elevated urinary albumin:creatinine ratio (ACR) have increased risk of heart failure. We hypothesized this was because of cardiac tissue changes rather than silent coronary artery disease. METHODS AND RESULTS In a case-controlled observational study 130 subjects including 50 ACR+ve diabetes mellitus patients with persistent microalbuminuri...

A 76-year-old patient with a medical history of hypertension, type 2 diabetes mellitus and moderate valvular aortic stenosis underwent cephalic DDD pacemaker implantation because of fatigue and a 3rd degree atrioventricular block with a ventricular escape rhythm of 45 beats per minute. After implantation, he complained about stabbing chest pains. A chest radiograph did not reveal any signs of a...

Vascular endothelial dysfunction is a basic etiologic factor for the development of late clinical complications in patients with diabetes mellitus type 1, such as diabetic retinopathy, diabetic nephropathy (which is characterized at the very beginning by microalbuminuria), and left ventricular cardiac dysfunction. The aims of this study were to determine the prevalence of asymptomatic left vent...

OBJECTIVES To examine the association between (1) comorbid conditions related to diabetes mellitus, clinical findings on arrival at the hospital, and characteristics of the myocardial infarction and (2) risk of heart failure, recurrent myocardial infarction, and mortality in the year after myocardial infarction in elderly 30-day survivors of myocardial infarction who had non-insulin- or insulin...

BACKGROUND Diabetes mellitus is capable of impairing the myocardial function. Several studies have documented the influential impact of diabetes mellitus on the left ventricular function. The right ventricular function plays a significant role in the overall myocardial contractility; hence, this study was undertaken to evaluate the effect of diabetes mellitus type II on the right ventricular fu...

OBJECTIVE This study aimed to determine the potential impact of type 2 diabetes mellitus on left ventricular dysfunction and the development of calcified aortic valve disease using a dyslipidemic mouse model prone to developing type 2 diabetes mellitus. APPROACH AND RESULTS When compared with nondiabetic LDLr(-/-)/ApoB(100/100), diabetic LDLr(-/-)/ApoB(100/100)/IGF-II mice exhibited similar d...

Diabetes mellitus, a disease that has been reaching epidemic proportions, is an important risk factor to the development of cardiovascular complication. Diabetes causes changes within the cardiac structure and function, even in the absence of atherosclerotic disease. The left ventricular diastolic dysfunction (VE) represents the earliest pre-clinical manifestation of diabetic cardiomyopathy, pr...