background and objective: recent studies have shown that not only the quantity, but also the quality of dietary fatty acids can affect lipid parameters. elaidic acid is a major hydrogenated by-product of vegetable oil play a role in the development of cardiovascular disease, especially atherosclerosis, through changing lipid profile and increase in inflammation and inflammatory factors. on the ...

INTRODUCTION The studies suggest that trans fatty acids are the most harmful type of fatty acids, and their ingestion leads to an increase in oxidative stress, changes in the plasma levels of LDL cholesterol, and a reduction in n-6 and n-3 fatty acids utilization. The objective of this study was to determine the concentration profiles of elaidic and vaccenic acids in maternal blood plasma in th...

A previous study showed that oleic acid was converted by mixed ruminal microbes to stearic acid and also converted to a multitude of trans octadecenoic acid isomers. This study traced the metabolism of one of these trans C18:1 isomers upon its incubation with mixed ruminal microbes. Unlabeled and labeled (18-[13C]trans-9 C18:1) elaidic acid were each added to four in vitro batch cultures with t...

Human red cell membrane Ca2+-stimulatable, Mg2+-dependent adenosine triphosphatase (Ca2+-ATPase) activity and its response to thyroid hormone have been studied following exposure of membranes in vitro to specific long-chain fatty acids. Basal enzyme activity (no added thyroid hormone) was significantly decreased by additions of 10(-9)-10(-4) M-stearic (18:0) and oleic (18:1 cis-9) acids. Methyl...

We investigated the applicability of FTIR-spectroscopy as a high throughput screening method for detection of biochemical changes in intact liver cells in bulk upon fatty acid exposure. HepG2 cells adapted to serum free (HepG2-SF) growth were exposed to four different fatty acids, three octadecenoic acids, differing in cis/trans-configuration or double bond position (oleic acid, elaidic acid an...

The fatty acid composition was evaluated in field grown sesame cultivars (Sesamum indicum L.) at New Developmental Farm Agriculture University, Peshawar, KPK Pakistan during summer 2012. The experiment was laid out in RCBD with split plot arrangement having four replications each. Two sesame cultivars viz., local black and local white were sown at different dates i.e. 20 June, 10 and 30 July, a...

introduction: nonalcoholic fatty liver disease (nafld) is a global disease which its prevalence is about 10-35%. several factors are involved in the pathogenesis of the disease. the present study was conducted to evaluate the effect of fasting during ramadan on plasma free fatty acids in patients with nafld.methods: this cross-sectional study was performed during the month of ramadan in june-ju...

Dietary fatty acids have a profound impact on atherosclerosis, but mechanisms are not fully understood. We studied the effects of a saturated fat diet supplemented with fish oil, trans10,cis12 conjugated linoleic acid (CLA), or elaidic acid on lipid and glucose metabolism and liver protein levels of APOE*3 Leiden transgenic mice, a model for lipid metabolism and atherosclerosis. Fish oil lowere...

Abstract This study aims to examine the effect of ultrasonic-assisted extraction method on yield oil and profile fatty acid from microalga yeast. The cultivated was identified genetically as Thraustochytrium multirudimentale MAST-1 yeast Rhodotorula mucilaginosa KAST-1. oils were extracted dried biomass by solvents using modified Bligh Dyer (BD) method. Before extraction, material underwent ult...

BACKGROUND Altered lipid metabolism and plasma fatty acid (FA) levels are associated with colorectal cancer. Obesity and elevated waist circumference (WC) increase the likelihood of developing precancerous colon adenomas. METHODS Venous blood was collected from 126 males, ages 48 to 65 years, who received routine colonoscopies. Plasma phospholipid (PPL) FAs were isolated, derivatized, and the...