We report a self-contained electrochemical enzyme linked immunosorbent assay in microchannel devices constructed from low temperature co-fired ceramic with screen-printed gold for fast and sensitive assays. No one has previously reported a device constructed from these materials for combined immobilization and electrochemical detection. These low temperature co-fired ceramic microchannel device...

ABSTRACT We report a novel signal amplification strategy integrated into a microfluidic paper-based electrochemical immunodevice to perform multiplexed measurement of cancer biomarkers. The signal amplification was achieved by using graphene to modify the immunodevice surface to accelerate electron transfer and silica nanoparticle as a tracing tag to label signal antibodies. Accurate, rapid, si...

We propose an RLC model for PEDOT:PSS electrochemical transistors to interpret the persistent oscillating currents observed in experiments. The electrochemical reaction is represented by an inductor in the equivalent circuit. The simulation results show that an electrochemical device can be operated as normal transistors or oscillators under different voltage bias. This model predicts that anal...

We have previously reported a local redox cycling-based electrochemical (LRC-EC) system for the incorporation of many electrochemical sensors into a small chip device. In the present study, a new type of LRC-EC chip device was fabricated for the detection of a droplet array. To detect electrochemically redox compounds in droplets, Pt pseudo-reference/counter electrodes were incorporated into th...

Miniaturized Electrochemical cell platforms are developed using two different approaches, namely surface and bulk micromachining technologies. Gold is used as the working electrode layer in both cases. In bulk micromachined device, electrodes are formed in the cavity created on silicon using KOH etching process while the cavity is formed using SU -8 epoxy photoresist on top of the electrodes in...

In this work, TiO2 nanostructures were grown on titanium thin films by electrochemical anodizing method. The bipolar resistive switching effect has been observed in Pt/TiO2/Ti device. Resistive switching characteristics indicated the TiO2 nanotubes are one of the potential materials for nonvolatile memory applications.  Increasing anodizing duration will increase nanotube lengths which itself c...

ABSTRACT In this study, we developed a novel device consisting of 32 row and 32 column electrodes on a single chip for highthroughput electrochemical detection. The row and column electrodes were orthogonally arranged and connected to interdigitated array (IDA) electrodes at individual crossing points to form 1024 (32 × 32) sensor points. Electrochemical responses from each of the 1024 sensors ...

Miniaturization and integration of chemical devices into modules that are dimensionally comparable with electronic chips (Lab on Chip) is nowadays developing worldwide. The aim of our work was to suggest and optimize the best conditions for fabrication of TFT sensor due to its sensitivity and low experimental deviations. New electrochemical analytical device was developed to ensure certain know...

An electrochemical 'Lab-on-a-chip' for water toxicity detection is presented. This miniaturized device containing an array of nano liter electrochemical cells, which integrates bacteria and can emulate physiological reactions in response to different chemicals. Bacteria, which have been genetically engineered to respond to environmental stress, act as a sensor element and trigger a sequence of ...

We have previously developed a local redox cyclingbased electrochemical (LRC-EC) chip device for highthroughput electrochemical detection [1-2]. In the LRCEC chip device, row and column electrodes are arranged orthogonally and these electrodes are connected to interdigitated array (IDA) electrodes to form n crossing points with only 2n bonding pads for external connection. Local redox cycling c...