Introduction Magnetic fields are capable of altering the trajectory of electron beams andcan be used in radiation therapy.Theaim of this study was to produce regions with dose enhancement and reduction in the medium. Materials and Methods The NdFeB permanent magnets were arranged on the electron applicator in several configurations. Then, after the passage of the electron beams (9 and 15 MeV Va...

background: exposure to ionizing radiation is known to induce oxidative stress followed by damage to critical biomolecules like lipids, proteins and dna through radiolysis of cellular water. since radiation has been widely used as an important tool in therapy of cancer, the detailed investigation regarding the dna damage and repair kinetics would help to predict the radiation sensitivity of cel...

Mycosis fungoides (MF), also known as Alibert-Bazin syndrome or granuloma fungoides, are a common subset of cutaneous T-cell lymphoma, with peak incidence in the 55~60 years age range. Radiation therapy is the most effective treatment method of MF, these dramatic responses of low dose X-ray therapy to MF were reported by Sholtz in 1902. Radiation therapy induces cell death predominantly by apop...

Background: Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers.Objective: The aim of this study is to understand characteristics of secondary electrons generated from interaction of gold nanoparticles GNPs with x-rays as a function of nanoparticle size and beam energy and ...

For over 50 years, electron beams have been an important modality for providing an accurate dose of radiation to superficial cancers and disease and for limiting the dose to underlying normal tissues and structures. This review looks at many of the important contributions of physics and dosimetry to the development and utilization of electron beam therapy, including electron treatment machines,...

In the treatment of superficial lesions with 8-13 MeV electrons, lead shields are often used to protect the underlying tissue. Measurements were made with film and ion chamber to analyse various aspects of external and internal shielding in electron beam therapy. Data were obtained on the thickness of lead required for shielding, the effect of blocking on dose-rate, electron-backscattering from...