PURPOSE To evaluate the 6-month safety and efficacy of ziv-aflibercept intravitreal injections for treating exudative age-related macular degeneration. METHODS Fifteen patients with unilateral exudative age-related macular degeneration were enrolled. The best-corrected visual acuity was measured and spectral domain optical coherence tomography was performed at baseline and monthly. Full-field...

To evaluate the effect of chlorogenic acid supplementation in patients with retinitis pigmentosa, we evaluated objective change in visual function with multifocal electroretinography, along with visual acuity, visual field, standard electroretinography, and contrast sensitivity. Eighteen patients diagnosed with retinitis pigmentosa were enrolled in this prospective, non-comparative, single-arm ...

PURPOSE To evaluate macular function by focal electroretinography and fluorescein angiography (FA) in patients with neovascular age-related macular degeneration submitted to verteporfin photodynamic therapy (VPT). METHODS Prospective study involving 22 patients with age-related macular degeneration and predominantly classic subfoveal neovascular membrane, in non consecutive series, treated wi...

This report describes the typical manifestations of chloroquine retinopathy with some advanced new technology. A series of examinations were performed on the patients, including the fundus fluorescein angiography, optical coherence tomography, GDxVCC Nerve Fiber Analyzer, full-field electroretinography, multifocal electroretinography and visual field examinations, to provide a better understand...

Multifocal electroretinography (mfERG) was developed by Sutter and Tran1 and has since revolutionized objective functional assessment of retinal diseases. In contrast to full-field electroretinography (ERG), which measures the electrical activity of the entire retina, mfERG allows simultaneous measurements of multiple responses at different retinal locations, thus enabling topographic mapping o...

Electroretinographic (ERG) investigations are conventionally performed by using corneal or conjunctival recording electrodes. Both types have to be placed in contact with the eye, resulting invasive and providing discomfort for the patient. This paper presents a simple technique to detect ERG potentials non-invasively. It relies on the use of a conducting liquid between the eye and an external ...