OBJECTIVES The purpose of this study was to determine the association of family history of peripheral artery disease (PAD) with PAD prevalence and severity. BACKGROUND PAD is a significant public health problem. Shared genetic and environmental factors may play an important role in the development of PAD. However, family history of PAD has not been investigated adequately. METHODS The San D...

Lower extremity peripheral arterial disease (PAD) is prevalent in the Medicare population and is associated with high rates of myocardial infarction, stroke, amputation, and death. Nevertheless, national health expenditures for PAD are not known. We hypothesized that PAD-related costs are high, increase with age, and that treatment rates would be less than known PAD prevalence. The objective wa...

A 7.1-kbp DNA fragment isolated from a wild strain of Klebsiella oxytoca was sequenced, leading to the identification of 10 open-reading frames (ORFs), including a 504-bp Pad gene. The Pad gene of the Gram-negative bacterium was subsequently expressed in Escherichia coli as a chimeric Pad. The deduced amino acid (AA) sequence of the Pad gene from wild-type K. oxytoca showed approximately 50% ho...

OBJECTIVE Low levels of fetuin-A, a systemic calcification inhibitor, are linked to mortality in patients on dialysis. In contrast, elevated fetuin-A is associated with cardiovascular events in non-renal patients. We investigated fetuin-A in patients with type 2 diabetes and peripheral arterial disease (PAD). RESEARCH DESIGN AND METHODS We studied fetuin-A in 76 patients with PAD and normal g...

the aim of this study was to find any structural differences between the digital pads of forelimbs and hind limbs as well as more careful investigation of the internal and external structures of the toe-pad. in this study, pad morphology and cytology in litoria caerulea is described using sem, tem and light microscopy. at the gross anatomical level, toe-pads in hind limbs were subdivided into m...

We describe a collection of Pad e-type methods for accelerating the convergence of sequence of functions. The construction and connections of Pad e’s methods with other similar methods are given. We examine the e ectiveness of these new methods, namely integral Pad e approximant, modi ed Pad e approximant and squared Pad e approximant together with the well-established methods, namely functiona...