Abstract Bisphenol A (BPA) is a monomer used in the production of polycarbonate, polymer commonly found plastics, epoxy resins and thermal papers. The presence BPA food, water, air dust has been great concern recent years not only due to environmental ecological issues but also because its supposed risk public health related mutagenic carcinogenic potential. In this study we evaluated toxicity ...

objective: this study aimed to investigate the effects of royal jelly (rj) on catalase, total antioxidant capacity and embryo development in adult mice treated with oxymetholone (oxm). materials and methods: in this exprimental study, 32 male and 96 female adult naval medical research institute (nmri) mice (7-9 weeks of age) with a ratio of 1:3 for fertilization purposes were randomly divided i...

The toxicity of three PCB congeners having different structural characteristics was studied using water exposures and the embryos of two sea urchin species, Strongylocentrotus purpuratus (purple sea urchin) and Lytechinus pictus (white sea urchin). Biological effects were assessed using two endpoints: percentage of normal embryo development and mitotic rate. Differential toxicity of the congene...

Background Quantum dots (QDs) are new types of fluorescent materials for biological labeling. QDs toxicity study is an essential requirement for future clinical applications. Therefore, this study aimed to evaluate cytotoxic effects of CdSe: ZnS QDs on male reproductive system. MaterialsAndMethods In this experimental study, the different concentrations of CdSe: ZnS QDs (10, 20 and 40 mg/kg) we...

background: quantum dots (qds) are new types of fluorescent materials for biological labeling. qds toxicity study is an essential requirement for future clinical applications. therefore, this study aimed to evaluate cytotoxic effects of cdse: zns qds on male reproductive system. materials and methods: in this experimental study, the different concentrations of cdse: zns qds (10, 20 and 40 mg/kg...

BACKGROUND The promulgation and diversification of micromanipulation procedures which open the zona pellucida of the oocyte or early embryo is steadily increasing the chance that zygotes will encounter infectious viral agents or gene transfer vectors derived from these agents. Such interactions could lead to toxic effects on the embryo or to insertion of foreign genes into the germ line. Adenov...

Fish embryos are widely used as an alternative model to study toxicity in vertebrates. Due to their complexity, embryos are believed to more resemble an adult organism than in vitro cellular models. However, concerns have been raised with respect to the embryo's metabolic capacity. We recently identified allyl alcohol, an industrial chemical, to be several orders of magnitude less toxic to zebr...

Ochratoxins, and particularly ochratoxin A (OTA), are toxic fungal-derived contaminants of food and other agricultural products. Growing evidence supports the degradation of OTA by chemical, enzymatic and/or microbial means as a potential approach to remove this mycotoxin from food products. In particular, hydrolysis of OTA to ochratoxin α (OTα) and phenylalanine is the presumptive product of d...