Three-dimensional ultrasound (3D US) is a new imaging modality, which is being introduced into clinical practice. Although this technique will not probably replace two-dimensional ultrasound, it is being increasingly used. It has been reported that 3D US is a very high reproducible technique. The endometrium has been paid special attention when using this technique. The aim of this paper is to ...

The implantation of embryo depends on the quality of the embryo and the receptivity of the endometrium. While the factors affecting embryo quality were optimized, the implantation rates did not reach the desirable levels. This directs the blaming for endometrial receptivity which already has been affected by supra-physiological levels of hormone, namely estradiol, in controlled ovarian hypersti...

ndometrial vasculature has been shown to play an important role in the early endometrial response to the implanting blastocyst, and vascular changes may contribute to uterine receptivity . the aim of this study was to investigate the role of endometrial and subendometrial vascularity and thickness in uterine receptivity in infertile women treated with assisted reproductive technologies (art). a...

STUDY QUESTION Does the combined oral contraceptive pill (COCP) change endometrial gene expression when used for cycle programming? SUMMARY ANSWER COCP used for scheduling purposes does not have a significant impact on endometrial gene expression related to endometrial receptivity. WHAT IS KNOWN ALREADY Controversy exists around COCP pretreatment for IVF cycle programming, as some authors c...

BACKGROUND Although embryo implantation is a prerequisite for human reproduction, it remains a poorly understood process. The molecular mechanisms regulating endometrial receptivity and/or embryo implantation are still largely unclear. METHODS Pubmed and Medline literature databases were searched for articles in English published up to December 2013 with relevant keywords including 'endometri...

BACKGROUND Implantation in humans involves cross talk between an active blastocyst and receptive endometrium. The role of the endometrial receptors in this complex embryo-maternal interaction is still unclear. We tested gene and protein expression of endometrial receptors (Progesterone receptor (PR) and c-Met) and the effect of theses receptors in endometrial receptivity. METHODS Two endometr...

BACKGROUND The use of fertility regulating drugs is limited among various socio-ethnic groups due to limited knowledge about their mechanism of action. This study investigates the effect of levonorgestrel and mifepristone on attachment of human embryos to an in vitro endometrial construct. METHOD Three-dimensional endometrial constructs were established by co-culturing early luteal phase huma...

background: aggressive embryo and receptive endometrium are necessary for successful implantation. on this time endometrium transformates to receptive state, which permits embryonic implantation. studies about embryonic implantation and endometrial receptivity are always a hot spot in the field of reproductive medicine. objective: to investigate the expression pattern of meis1 during peri-impla...

OBJECTIVE HOXA10 is an essential regulator of endometrial receptivity. To determine the effect of GnRH antagonists on endometrial receptivity, we assessed endometrial HOXA10 expression in GnRH antagonist, GnRH agonist, and natural cycles. DESIGN Prospective case-control study. SETTING University academic medical center. PATIENT(S) Nineteen subjects were included: 12 subjects underwent con...

Implantation in humans is a complex process that involves embryo apposition and attachment to the maternal endometrial epithelium, traversing adjacent cells of the epithelial lining, and invasion into the endometrial stroma. These processes involve a variety of molecules which are not unique in themselves, but play unique roles in the process of implantation. The molecular dialogue that occurs ...