Methods Four centres in Spain and France enrolled in 3 intervention trials of MRSA control performed universal MRSA screening on admission to intensive care units (ICUs), surgical wards and rehabilitation units from August 2008 to March 2010. Demographic and comorbidity data were collected. Univariate and multivariate logistic regression analyses were used to identify risk factors for unknown M...

OBJECTIVE To test whether strict implementation of a standardised protocol for the management of malaria and provision of a financial incentive for health workers reduced mortality. DESIGN Randomised controlled intervention trial. SETTING Paediatric ward at the national hospital in Guinea-Bissau. All children admitted to hospital with severe malaria received free drug kits. PARTICIPANTS 9...

We derive the nonparametric maximum likelihood estimator (NPMLE) of the distribution of the test items using a random, right-censored sample combined with an additional right-censored, residual-lifetime sample in which only lifetimes past a known, fixed time are collected. This framework is suited for samples for which individual test data are combined with left-truncated and randomly censored ...

BACKGROUND The effects of the Liverpool Care Pathway (LCP) have never been investigated in older patients dying in acute geriatric hospital wards and its content and implementation have never been adapted to this specific setting. Moreover, the LCP has recently been phased out in the UK hospitals. For that reason, this study aims to develop a new care programme to improve care in the last days ...

Actively engaging communities in effective partnerships for the design and implementation of HIV prevention research is vital to the successful conduct of ethically robust, locally-appropriate clinical trials in developing countries. This is especially true in vulnerable at-risk sub-populations, where definitions of "community", "participation" and "representation" can be difficult to apply. Th...

The Maximin Efficiency-Robust Test idea of Gastwirth (1966) was to maximize the minimum asymptotic power (for fixed size) versus special local families of alternatives over some specially chosen families of score statistics. This approach is reviewed from a general decision-theoretical perspective, including some Bayesian variants. For two-sample censored-data rank tests and stochastically orde...

Using a rich longitudinal data set from birth, we explore three estimation issues related to academic performance analysis. Our paper primarily examines the effect of omitting childhood and teenage characteristics (childhood ability, parental resources at different times and peer effects), which are traditionally unavailable in data sets. Additionally, we explore the potential endogeneity of pr...