The Retinoblastoma is the most common primary intraocular cancer in children and a rare disease; is characterized by a malignant tumor, which originates in the unripe retinoblasts. Its distribution is 3% of deaths in children, the age is essentially because 95% of the retinoblastoma’s have been detected, or diagnosed before the age of 5 years. The males were a high predisposition and the tumor ...

BUJO | VOL 2 | ISSUE 1 | SEPTEMBER 2014 Abstract Retinoblastoma often sparks interest because the underlying cancer gene mutation was the first to be identified and cloned. However, apart from its genetic intrigue, the condition illustrates the health disparities between more and less developed countries. We present a case of retinoblastoma in a 6 month old boy who presented with left eye leuko...

retinoblastoma is the most common primary intraocular malignancy in childhood. enucleation remains the treatment of choice in many children because the eye can not be salvaged with any other treatment modality. in some cases after enucleation etiologies other than retinoblastoma are detected in histopathologic review (pseudoretinoblastomas). this study aims to evaluate the prevalence and etiolo...

purpose: to introduce a case of neglected advanced retinoblastoma. case report: a 6 year old girl presented with a large orbital mass enlarging over her cheek on the right side. she underwent exenteration and histopathologic evaluation. a diagnosis of retinoblastoma was made with free margins. this case presents a rare form of retinoblastoma with extensive local progression but no metastasis or...

BACKGROUND As cure rates for retinoblastoma have improved, it is clear that patients with hereditary retinoblastoma experience increased risk of subsequent malignant neoplasms (SMNs). METHODS Using the Surveillance, Epidemiology and End Results (SEER) database, we evaluated risk of SMNs in survivors or retinoblastoma. Standardized mortality ratios (SMRs) were calculated to compare number of d...

OBJECTIVE To study the epidemiology of retinoblastoma in Taiwan from 1998 to 2011. DESIGN This was a retrospective population-based cohort study using the Taiwan National Health Insurance Research Database. RESULTS The present study included 154 patients (92 males, 62 females) with retinoblastoma and the documented overall retinoblastoma incidence was 1 in 17 373 live births without a notab...

  Background and Objectives: Retinoblastoma is the most common intraocular pediatric malignancy. Angiogenic factor expression such as VEGF (vascular endothelial growth factor) in retinoblastoma can be confirmatory angiogenic potential of this tumor. This study was performed to determine the role of angiogenesis in local invasion of retinoblastoma and its correlation with patients’ sur...

retinoblastoma is the most common intraocular neoplasm in children. glial tumor of the retina and optic nerve head are considered to be congenital and are therefore classified as hamartomas. concurrent occurrence of these tumors in one eye is uncommon and by reviewing the studies, a few cases have been reported. we report a 9 years old boy with eye enucleation and concurrent occurrence of retin...

purpose : to evaluate the effectiveness of chemoreduction (crd) for globe saving in patients with intraocular retinoblastoma methods : in this interventional case series all patients with intraocular retinoblastoma were included and classified according to the international classification of retinoblastoma (icrb) from group a to e. six cycles of intravenous vincristine, etoposide and carboplati...

retinoblastoma is a retinal malignant tumor that occurs in early childhood. the annual incidence of retinoblastoma is approximately one per 14 000 live births. 250 to 300 new cases are reported in the united states each year. it develops due to inactivation of both alleles of the retinoblastoma susceptibility (rb1) gene. all hereditary cases (55%) are with bilateral and multifocal lesions, but ...