microglia is the effector cell of the innate immune system in central nervous system (cns). these cells mediate inflammatory responses in injuries. besides external factors, microglial function is also controlled by internal factors, including epigenetic regulations. mechanisms of epigenetic regulation mainly consist of dna methylation, histone modifications and use of non-coding rnas. recent s...

BACKGROUND Epigenetics, which is just beginning to attract public attention and policy discussion, challenges conventional understanding of gene-environment interaction and intergenerational inheritance and perhaps much more besides. QUESTION Does epigenetics challenge modern political ideologies? METHODS I analyzed the narratives of obesity and epigenetics recently published in the more li...

Epigenetics is characterized as hereditary changes in gene activity and expression that occur without alteration in DNA genomic sequence. It is known that epigenetics corresponds basically by two majority modifications: DNA methylation and histone modifications. Epigenetics events are reversible without primary DNA base sequence changes, resulting in possible modulation of the gene expression. ...

With rapid evolution ongoing in the field of epigenetics, clinicians, hindered by time constraints, are often unable to adequately keep up with the new developments that apply to their patients and practice. Epigenetics in Psychiatry aims to tackle this precise problem. With near absolute completeness, the text covers not only the most recent developments in epigenetics related to psychiatric d...

The concept of chromatin as a complex nucleic acid and proteins in the cell nucleus was developed by cytologists biochemists late 19th century. It starting point for biochemical research on DNA nuclear proteins. Interest declined rapidly at beginning 20th century, but few decades later new focus emerged, which not only related to its structure, also function gene regulatory processes developmen...

Epigenetics is the study of changes in gene expression caused by mechanisms other than changes in the DNA itself. The field is rapidly growing and being widely promoted, attracting attention in diverse arenas. These include those of the social sciences, where some researchers have been encouraged by the resonance between imaginaries of development within epigenetics and social theory. Yet, sust...

With rapid evolution ongoing in the field of epigenetics, clinicians, hindered by time constraints, are often unable to adequately keep up with the new developments that apply to their patients and practice. Epigenetics in Psychiatry aims to tackle this precise problem. With near absolute completeness, the text covers not only the most recent developments in epigenetics related to psychiatric d...

Correspondence to: Carolyn E. Banister; Email: [email protected] The study of epigenetics has experienced exponential growth in the past 15 years and continues to be a major focus of study across biological disciplines. A new reference text Epigenetics: A Reference Manual, published by Caister Academic Press and edited by Jeffrey M. Craig and Nicholas C. Wong (Developmental Epigenetics...

cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irreversible transformation of cells with a new anarchic behavior. tumor suppressor inactivation and/or oncogene activation will lead to tumorigenesis. based on the genetic alteration in germ or somatic cells, the affected person will have a different fate of cancer incidence or inheritable cancer su...

The new science of epigenetics has raised hopes of an embrace of greater plasticity and variation within the biology of sex, gender, and sexuality than previously appreciated. This essay describes and analyzes the integration of epigenetics research into the scientific study of core biological pathways related to sex, gender, and sexuality in the brain in the post-Human Genome Project era. Thro...