Physiologically based models are attractive for seizure detection, as their parameters can be explicitly related to neurological mechanisms. We propose an early seizure detection algorithm based on parameter identification of a neural mass model. The occurrence of a seizure is detected by analysing the time shift of key model parameters. The algorithm was evaluated against the manual scoring of...

Abstract Purpose of Review Sudden Unexpected Death in Epilepsy (SUDEP) is the commonest cause epilepsy-related premature mortality people with chronic epilepsy. It most devastating epilepsy outcome. We describe and discuss risk factors possible pathophysiological mechanisms to elucidate preventative strategies avert SUDEP. Recent Findings death accounts for a significant proportion compared gen...

Epilepsy is a common neurological disease with various seizure types, complicated etiologies, and unclear mechanisms. Its diagnosis mainly relies on clinical history, but an electroencephalogram also crucial auxiliary examination. Recently, brain imaging technology has gained increasing attention in the of epilepsy, conventional magnetic resonance can detect epileptic foci some patients epileps...

Epilepsy is one of the most common neurological disorders-approximately one in every 100 people worldwide are suffering from it. The electroencephalogram (EEG) is the most common source of information used to monitor, diagnose and manage neurological disorders related to epilepsy. Large amounts of data are produced by EEG monitoring devices, and analysis by visual inspection of long recordings ...

post-traumatic epileptic seizure is a common complication of brain trauma including military injuries. we present clinical characteristics and correlates of post-traumatic epilepsy in 163 head-injured veterans suffering from intractable epilepsy due to blunt or penetrating head injuries sustained during the iraq-iran war. the medical records of 163 war veterans who were admitted by the epilepsy...

OBJECTIVE Around 1% of the world's population is affected by epilepsy, and nearly 25% of patients cannot be treated effectively by available therapies. The presence of closed-loop seizure-triggered stimulation provides a promising solution for these patients. Realization of fast, accurate, and energy-efficient seizure detection is the key to such implants. In this study, we propose a two-stage ...

Epilepsy is associated with a higher rate of premature death than the general population, and the commonest cause of epilepsy mortality is sudden unexpected death in epilepsy (SUDEP). It is difficult to quantify because of the variable reporting of this cause of death. Death occurs due to autonomic deregulation of cardio-respiratory pathways as a result of seizures. Measures to reduce cardio-re...

This retrospective study reviewed the charts of children with epilepsy who were followed up in pediatric neurology clinic King Fahad Hospital Al-Baha region, Saudi Arabia, between January 2015 and August 2022. Children 1 to 14 years age had epilepsy, as per International League against Epilepsy (ILAE) definition, received anti-seizure medication a seizure-free period at least two months before ...

Acquired epilepsy (i.e., after an insult to the brain) is often considered to be a progressive disorder, and the nature of this hypothetical progression remains controversial. Antiepileptic drug treatment necessarily confounds analyses of progressive changes in human patients with acquired epilepsy. Here, we describe experiments testing the hypothesis that development of acquired epilepsy begin...