introduction bnct is an effective method to destroy brain tumoral cells while sparing the healthy tissues. the recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. in this paper, it is indicated that using d-t neutron source and optimizing of beam shaping assembly (bsa) leads to treating brain tumors in a reasonable time where all iaea ...

PURPOSE This study was undertaken to explore the effects of the jaws and the MLC openings on the neutron dose equivalent (DE) at the maze door and neutron flux at the patient plane. METHODS The neutron dose equivalent was measured at the maze entrance door of a 15 MV therapy linear accelerator room. All measurements were performed using various field sizes up to 40 cm × 40 cm. Activation dete...

Radiation sensitive polymer gels are among the most promising three-dimensional dose verification tools developed to date. Polymer gel dosimeter known by the acronym MAGIC has been tested for evaluation of its use in boron neutron capture (BNCT) dosimetry. We irradiated a large (diameter 10 cm, length 20 cm) cylindrical gel phantom in the epithermal neutron beam of the Finnish BNCT facility at ...

Over the past decade, there has been a continued interest in the development of Boron Neutron Capture Therapy (BNCT) as a potential treatment for cancerous tumours and especially certain brain tumours. In this method, advantage is taken of the nuclear properties of certain elements such as boron. A special boron carrier drug, designed to be selectively taken up by the cancer cells, is administe...

Neutron penetration in tissue is a major limitation of thermal NCT, as such much work has centered upon the epithermal neutron beam in an effort to improve this situation. Further gains in neutron flux penetration, and thus therapeutic ratios, are possible if natural water is replaced with heavy water prior to therapy. Applying MCNP to a heterogeneous ellipsoidal skull/brain model, advantage de...

In the framework of the Italian BNCT research program, the low-power (5 kW), fast-flux, TAPIRO research reactor, located at the ENEA Casaccia Centre near Rome, is foreseen to be implemented as the national facility devoted to supply an epithermal neutron beam required for malignant brain tumor treatment[1]. The feasibility to provide both thermal and epithermal suitable neutron beams in the mai...

Nowadays neutron capture therapy looks very promising method of cancer treatment, especially for brain tumors by reason of selective damage cancer cells. Treatment effect of this method based on neutrons nuclear reaction with nuclides B, Gd. These nuclides have high cross-section of interaction with thermal neutrons. Unfortunately, thermal neutrons could enter only in near surface tissue and co...

Introduction BNCT is an effective method to destroy brain tumoral cells while sparing the healthy tissues. The recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. In this paper, it is indicated that using D-T neutron source and optimizing of Beam Shaping Assembly (BSA) leads to treating brain tumors in a reasonable time where all IAEA ...

The 1MW pool-type Portuguese research reactor (RPI) was converted from using highly enriched uranium (HEU) to using low enriched uranium (LEU) fuel in September 2007. Although the new LEU core has the same number of fuel assemblies as the first HEU core, it has three assemblies less than the last HEU core and also has a different arrangement of the beryllium reflectors. Therefore, the primary i...