conclusions the findings of the meta-epidemiological study support that ebv infection may increase the risk of breast cancer. nested case-control studies are required in the future. results a total of 20 case-control studies were selected, and the total numbers of subjects in the case and control groups were 1947 and 1010, respectively. the findings of this meta-analysis revealed that ebv infec...

introduction epstein-barr  virus  (ebv)  infection  can  present  with  a  variety  of  manifestation. case report  here  we  present  a  case  of  a  7  year- old  immunocompetent  girl  who  came  with  acute  abdominal  pain ,  had  echocardiographic  evidence  of  myocardial  dysfunction  and  finally  was  diagnosed  as  a  case  of  serologically  proven  acute  ebv  infection. conclusion...

the aim of this work was to see whether tamarin immunisation with recombinant vaccinia virus expressing epstein barr virus latent proteins could prime t cells which were, on activation, able to inhibit the outgrowth of epstein barr virus transformed cells in vitro. the vaccination appeared to be successful as all vaccinated tamarins developed vaccinia lesions. however, the vaccination protocol ...

background multiple sclerosis (ms) is a demyelinating condition affecting the central nervous system. although the cause of this condition is unknown, patients with ms seem to have genetic vulnerability to certain environmental factors such as infection that could trigger this condition. objectives we conducted this study to determine whether ms risk increases following primary infection with e...

BACKGROUND After acute infection of Epstein-Barr virus, Epstein-Barr virus-infected B cells survive but usually do not show clonal proliferation. However, Epstein-Barr virus-infected B cells occasionally acquire a proliferative capacity that provokes clonal lymphoproliferative disorders. We herein present a case with Epstein-Barr virus-infected CD30+ B cell and immunoglobulin G4+ plasmacytoid c...

Recent epidemiological and immunological studies provide evidence for an association between Epstein-Barr virus infection and multiple sclerosis, suggesting a role of Epstein-Barr virus infection in disease induction and pathogenesis. A key question in this context is whether Epstein-Barr virus-infected B lymphocytes are present within the central nervous system and the lesions of patients with...

background: colorectal cancer is one of the most common malignancies worldwide with more than one million new cases diagnosed each year . the aim of this study is to investigate the prevalence of herpes simplex virus and epstein-barr virus in patients with colorectal carcinomas and polyps in comparison with healthy subjects by using the polymerase chain reaction technique. methods: in this anal...

Infection with Epstein-Barr virus is the trigger for development of multiple sclerosis

epstein-barr virus (ebv) was discovered 50 years ago from an african burkitt lymphoma cell line. ebv-associated lymphoproliferative disorders (lpds) are life-threatening diseases, especially in children. in this article, we review ebv-associated lpds, especially in the area of primary immunodeficiency disease (pid). we searched pubmed for publications with key words including ebv infection, lym...