A 74-year-old woman was admitted to our unit with complaints of abdominal discomfort and heartburn over 2 months. She had a history of hypertension and celiac disease, but admitted that she did not comply with a gluten-free diet. She had no history of any medication, smoking, or drinking alcohol, and her family history was unremarkable. Physical examination findings were normal. Serological stu...

BACKGROUND Malignant melanoma in the gastrointestinal tract may be primary or metastatic. Mucosal melanoma is a quite rare and aggressive disease, growing hidden and diagnosed with a certain delay which makes treatment difficult. CASE REPORT The authors present the first patient with c-kit exon 11 mutated primary esophageal melanoma treated with oral tyrosine kinase inhibitor masitinib. A 55-...

The case of a 54-year-old man with primary malignant melanoma of the esophagus is described. The results of morphologic examination are presented, and the histogenesis of the tumor and the classification of melanomas are briefly discussed. Histologic examination suggested that this was a case of primary malignant melanoma of the esophagus arising from melanosis of the esophageal mucosa. Like me...

Since the introduction of sentinel node biopsy in 1990 as a minimally invasive surgical technique for the diagnosis of melanoma lymphatic metastases, the number of applications has expanded. We review applications and the current status of sentinel node biopsy in melanoma, breast, colon, gastric, esophageal, head and neck, thyroid, and lung cancer. Variations on techniques specific to each orga...

INTRODUCTION Primary malignant melanoma of the esophagus is a rare but highly aggressive tumor with poor prognosis. Surgical resection is the treatment of choice. However, some cases may be diagnosed with advanced inoperable disease. Palliative radiotherapy may be used to relieve symptoms caused by the esophageal tumor. CASE PRESENTATION We report on a case of advanced inoperable primary mali...

Primary malignant melanoma of the esophagus is a rare but aggressive tumor that accounts for <1% of all esophageal neoplasms.1 Worldwide, approximately only 250 cases have been published in the English literature to date,2 however, individual case reports have been described in the radiology literature.3,4 We report 2 male patients with histopathologically confirmed primary malignant melanomas ...

BACKGROUND Primary malignant melanoma of the oesophagus (PMME) is an uncommon tumor. PMME has an aggressive biological behavior, similar to melanomas developed elsewhere in the body. Most patients die from distant metastases, and the overall 5 year survival rate is approximately 4%. CASE PRESENTATION We report a rare case of a solitary pulmonary metastasis found 5 years after curative resecti...

Primary malignant melanoma of the esophagus (PMME) is a rare entity, representing only 0.1-0.2% of all esophageal malignancies. The most common location of melanoma in esophagus is in the middle to lower thoracic part. Dysphagia or retro sternal discomfort or pain is the most common initial presentation. It commonly metastasizes via hematogenic and lymphatic pathways. Esophagectomy and lymph no...

Primary malignant melanoma of esophagus is a rare but highly aggressive neoplasm, with an incidence less than 0.2% of all primary esophagus neoplasms. There are no clinical differences from other forms of esophagus cancer. Because initial symptoms are nonspecific, the patients are usually diagnosed at a late stage. The prognosis is poor, and curative effect seems disappointed. Several reports s...