BACKGROUND AND OBJECTIVES ADIAL ARTERY SPASM IS ONE OF THE MOST COMMON COMPLICATIONS OF TRANSRADIAL CORONARY ANGIOGRAPHY (TRA): the radial artery is prone to cathecholamine-induced contraction and radial pain during TRA could increase the sympathetic tone. The object of this study was to evaluate whether the eutectic mixture of local anesthesia (EMLA) cream, in addition to lidocaine infiltratio...

Various methods have been used to obtain blood samples from unrestrained rhinoceros. Without extensive prior training, the results are generally poor due to pain avoidance reactions. However a new dermal anesthesia technique previously used in humans, an eutectic mixture of lidocaine and prilocaine, made it possible to obtain blood samples from the ear veins of one male and two female white rhi...

Sentinel lymph node biopsy (SLNB) has been reliably accurate as a minimally invasive surgical alternative for identifying lymphatic breast metastasis. During mapping, the injection of a radioactive tracer or isosulfan blue dye to differentiate the SLN is acutely painful. The use of the eutectic mixture of lidocaine and prilocaine (EMLA) cream to reduce tracer injection pain has been reported an...

Placement of IV catheters is a painful and stressful procedure for children. J-Tip is a needle-less Food and Drug Administration approved injection system that can be used for delivery of local anesthetic before IV cannulation. In this study, we compared the effectiveness of J-Tip versus eutectic mixture of local anesthetics (EMLA) to facilitate IV cannulation and provide adequate analgesia bef...

Deep eutectic solvents (DES) are products of interaction betweensolid parent compounds resulting in a liquid at room temperature due to significantmelting point depression. Such phenomenon has been employed improve drugs’ biopharmaceuticalbehavior by including least one API as DES former produce therapeuticDES (THEDES). physicochemical characteristics affected those the parentcompounds. Investi...

Although the use of injectable anesthesia prior to subgingival scaling and root planing (SRP) reduces pain, many patients report fear and prolonged numbness of adjacent tissues. The aim of the present study was to compare the effects of a eutectic mixture containing 25 mg/g of lidocaine and 25 mg/g of prilocaine, injectable 2% lidocaine, topical 2% benzocaine and a placebo substance on reducing...

Electroneurography (ENoG) is an electrodiagnostic procedure used to evaluate facial nerve deficit. A problem with application, however, is pain. Several studies have demonstrated that topical application of the eutectic mixture of lidocaine and prilocaine has an anesthetic effect on superficial and deep tissues. The present study was intended to determine if successful anesthesia of the trigemi...

Background: EMLA cream is a eutectic mixture of Lidocaine and Prilocaine used to induce local anesthesia for dermatological procedures. Objective: This study was designed to evaluate the efficacy of EMLA cream in reducing the pain of intralesional injection of steroid in patients with alopecia areata. Patients and Methods: This study was carried out on 27 alopecia areata patients. The injection...