The aim of the study was to evaluate macular thickness and macular volume in unilateral and bilateral exfoliation syndrome and to compare them with exfoliative glaucoma and control eyes using optical coherence tomography. This prospective study included 114 subjects (228 eyes) divided into 4 groups according to the presence of exfoliation: 30 patients with unilateral syndrome, 24 patients with ...

PURPOSE To evaluate the association of lysyl oxidase like 1 (LOXL1) gene variants in Japanese patients with open-angle glaucoma. METHODS We evaluated the association of three LOXL1 variants (rs1048661, rs3825942, and rs2165241) in 142 Japanese patients with exfoliation syndrome (EX; n=59) and exfoliation glaucoma (EG; n=83) as well as in 251 control patients aged 70 years or older with primar...

The aim of the present study was to determine the level of Tumor necrosis factor-alpha in aqueous humor and serum of patients with pseudo exfoliation syndrome. The materials and methods in this study, we measured the level of Tumor necrosis factor-alpha, in aqueous and serum of patients with pseudo exfoliation syndrome and compared the findings with healthy controls. The Results are Regarding A...

EXFOLIATION SYNDROME Overview Exfoliation syndrome is the most widespread, classifiable cause of open-angle glaucoma worldwide.1 In this age-related disorder, fibrillar extracellular materials are produced by and accumulate in various ocular tissues (Figure 1). Friction between the anterior lens capsule and the iris disrupts the iris pigment epithelium, dispersing pigment throughout the anterio...

the witkop syndrome is a rare autosomal dominant disorder characterized by the absence of several teeth and abnormalities of the nails. this is the first report of a rare genetic tooth and nail syndrome diagnosed in a 2.5-year-old boy with early exfoliation of the primary canine, absence of the primary incisors, and nail dysplasia. a homozygous mutation was identified in 3’-utr of msx1 gene in ...

In the Eye Outpatient Department of H.P. Medical College Hospital, Simla, nine cases of capsular exfoliation affecting seventeen eyes were seen in the course of 6 months. Their main features are given in Table I (overleaf, pp. I22 and 123). All the patients were males between the ages of 6o and 76 years. The capsular exfoliation was associated with phakodonesis, iridodonesis, glaucoma, primary ...