background and objectives: biological scaffold resources composed of extracellular matrix (ecm) have been shown to make easy the practical remodeling of various tissues in both animal and human studies. the goal of current study was to make sheet form of ecm from sheep’s urinary bladder. methods: ecm was extracted from sheep’s urinary bladder according to standard method. scanning electron mic...

introduction as a tumor grows, the demand for oxygen and nutrients increases and it grows further if acquires the ability to induce angiogenesis. in this study, we aimed to present a two-dimensional continuous mathematical model for avascular tumor growth, coupled with a discrete model of angiogenesis. materials and methods in the avascular growth model, tumor is considered as a single mass, wh...

background: recurrence rate of rotator cuff tears is still high despite the improvements of surgical techniques, materials used and a better knowledge of the healing process of the rotator cuff tendons. large to massive rotator cuff tears are particularly associated with a high failure rate, especially in elderly. augmentation of rotator cuff repairs with extracellular matrix or synthetic patch...

 Background: Recurrence rate of rotator cuff tears is still high despite the improvements of surgical techniques, materials used and a better knowledge of the healing process of the rotator cuff tendons. Large to massive rotator cuff tears are particularly associated with a high failure rate, especially in elderly. Augmentation of rotator cuff repairs with extracellular matrix or synthetic patc...

background: integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. integrins are known to associate with a number of accessory molecules such as cd147 that may act to regu...

introduction: the cell surface glycoconjugate and extracellular matrix may mediate extracellular signals which decide the fate of the cells during tissue interactions. the proper development of cornea needs cellular interaction between surface epithelium, neural crest and developing lens. materials and methods: 50 pregnant rats were chosen and the embryos from pernatal day11-to 20 and postnatal...

background: gap-junctional intercellular communication (gjic) is implicated in physicological processes and it is vitally important for granulosa cell (gc) differentiation and oocyte growth. we investigated the expression of connexin 43 (cx43), a gap junctional protein, in normal and androstenedione-induced polycystic ovary (pco), the effects of androstenedione on cx43 expression, gjic and prog...