نتایج جستجو برای: factor x deficiency

تعداد نتایج: 1537001  

Journal: :Hamostaseologie 2009
Ina Hainmann J Oldenburg A Pavlova A Superti-Furga B Zieger

The genotype-phenotype relationship of compound heterozygous factor X deficiency in a young girl with severe factor X deficiency and bleeding symptoms is characterized. We identified a novel deletion of exon 6 and a missense mutation (c.856G>A, Val286Met) in exon 7 of the F10 gene leading to a compound heterozygous state and causing severe factor X deficiency. Therapeutic options for patients w...

Journal: :BMJ case reports 2011
Andreia Mascarenhas Marilene Eusébio Orquídea Freitas Teresa Almeida

Acquired factor X deficiency is an extremely rare situation. It has shown to be associated with systemic amyloidosis, respiratory mycoplasma infection, factor X inhibitors, antiphospholipid antibodies, vitamin K deficiency/liver disease as well as the use of certain medications (meropenem, valproic acid). The pathogenesis and transient nature of this deficit remain poorly understood. The author...

Journal: :Archives of disease in childhood 1980
S J Machin M R Winter S C Davies I J Mackie

An infant with a severe deficiency of factor X presened in the neonatal period with uncontrollable bleeding from heel prick sites, spontaneous bruising, and haematoma. The deficiency was controlled by infusions of dried human factors II, IX, and X concentrate; the half-life of the infused factor X material is only 18 hours. Despite prophylactic weekly infusions of factor X concentrate, the chil...

Abstract Background and Objectives Vitamin K-dependent clotting factor deficiency (VKCFD) is usually an acquired problem due to liver disease, malabsorption, and overdose of warfarin.  In the present paper the significance and role of vitamin K-dependent coagulation factors in menorrhagia were evaluated.   Case We present a rare case of 43 year woman with acquired vitamin K deficiency and se...

Journal: :Thrombosis and haemostasis 1998
A Hamasaki K Ishii K Yamaguchi M Sunamoto H Ozaki M Yanagita Y Wakatsuki H Horiuchi Y Nakahata T Kita

disease and/or platelet activation, and may not participate directly in pathogenesis. We conclude that raised sP-selectin indicates a poor prognosis among patients with peripheral artery disease. The wide range of values means that this marker alone is unlikely to be of value in defining the risk of disease progression in any individual subject. However, it may be useful as part of a panel of m...

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