Van Lunteren, Erik, and Michelle Moyer. Effects of DAP on diaphragm force and fatigue, including fatigue due to neurotransmission failure. J. Appl. Physiol. 81(5): 2214– 2220, 1996.—Among the aminopyridines, 3,4-diaminopyridine (DAP) is a more effective K1 channel blocker than is 4-aminopyridine (4-AP), and, furthermore, DAP enhances neuromuscular transmission. Because 4-AP improves muscle cont...

Among the aminopyridines, 3,4-diaminopyridine (DAP) is a more effective K+ channel blocker than is 4-aminopyridine (4-AP), and, furthermore, DAP enhances neuromuscular transmission. Because 4-AP improves muscle contractility, we hypothesized that DAP would also increase force and, in addition, ameliorate fatigue and improve the neurotransmission failure component of fatigue. Rat diaphragm strip...

OBJECTIVE The compressive tolerance of the cervical spine has traditionally been reported in terms of axial force at failure. Previous studies suggest that axial compressive force at failure is particularly sensitive to the alignment of the cervical vertebra and the end conditions of the test methodology used. The present study was designed to develop a methodology to combine the data of previo...

in asymmetric conflicts, great powers often adopt coercive strategies toward weak states. this strategy is a combination of threat, and limited and warning use of force if necessary to impact the opposite's strategy choice. given that the threats of the most powerful states are more effective because the penalty for target disobedience will be more intensive, it seems that the weak states ...

Building pounding occurs between two adjacent buildings with small gap or without sufficient separation distance. It leads to damage buildings during earthquake due to impact. Many researchers have investigated building pounding based on impact force reduction and energy dissipation increase, when two buildings collide with each other. In numerical investigations, using specific link element, i...

in this paper, dissimilar resistance spot welding of aisi 1075 eutectoid steel to aisi 201 stainless steel is investigated experimentally. for this purpose, the experiments are designed using response surface methodology and based on four-factor, five-level central composite design. the effects of process parameters such as welding current, welding time, cooling time and electrode force are inv...