he discovery of the anti-obesity hormone leptin (the name is derived from the Greek " leptos " meaning " thin "), the product of the ob gene, 1 has fuelled a recent surge of interest in the mechanisms regulating mammalian fat stores. Leptin, a 16 kD protein of 167 amino acids with a similar crystal structure to cytokines, 2 is produced primarily by white adipose tissue. 3 The hormone elicits ap...

Every click on a Web link is a leap of faith. When you click on the blue underlined text or on a picture on a Web page, there is always a [sometimes much too long] moment of suspense when you are waiting for the page to load. Until you actually see what is behind the link, you don’t know whether it will lead to the reward of another interesting page, to the disappointment of a “junk” page, or w...

A novel approach to the specification and verification of C programs through an annotation language that is a mixture between JML and the language of Isabelle/HOL is proposed. This yields three benefits: specifications are concise and close to the underlying mathematical model; existing Isabelle theories can be reused; and the leap of faith from specification language to encoding in a logic is ...