OBJECTIVE The aim of the present study was to compare between two antioxidant treatments in prevention of fenitrothion induced toxicity on rat parotid salivary gland. DESIGN Forty adult male Wistar rats with an average weight of 120-150 g were randomised into 4 groups, control (group I), fenitrothion administration (group II), fenitrothion administration 1h after green tea extract or Nigella ...

A bacterium capable of utilizing fenitrothion (O,O-dimethyl O-4-nitro-m-tolyl phosphorothioate) as a sole carbon source was isolated from fenitrothion-treated soil. This bacterium was characterized taxonomically as being a member of the genus Burkholderia and was designated strain NF100. NF100 first hydrolyzed an organophosphate bond of fenitrothion, forming 3-methyl-4-nitrophenol, which was fu...

Development of insecticide resistance has been a serious concern worldwide, whose mechanisms have been attributed to evolutionary changes in pest insect genomes such as alteration of drug target sites, up-regulation of degrading enzymes, and enhancement of drug excretion. Here, we report a previously unknown mechanism of insecticide resistance: Infection with an insecticide-degrading bacterial ...

   In this study, a method for extraction and preconcentration of trace amounts of organophosphorus pesticides (OPPs) in environmental water using magnetic solid phase extraction (magnetic-SPE) followed by high performance liquid chromatography (HPLC) with UV detection was developed. The magnetic carbon nanotube adsorbents (Fe3O4/CNT) were synthesized by grafting carbo...

An unblinded crossover study of fenitrothion 0.18 mg/kg/day [36 times the acceptable daily intake (ADI)] and 0.36 mg/kg/day (72 X ADI) administered as two daily divided doses for 4 days in 12 human volunteers was designed and undertaken after results from a pilot study. On days 1 and 4, blood and urine samples were collected for analysis of fenitrothion and its major metabolites, as well as pla...

A sensor, based on multi-wall carbon nanotubes modified glassy carbon electrode (MWCNT/GCE), was developed for determination of fenitrothion. Determining the surface area of MWCNT/GCE showed that this surface is three times more active than that of a glassy carbon electrode. The experimental parameters, such as the amount of MWCNTs, pH of the fenitrothion solution, preconcentration potential an...

The adsorptive stripping differential pulse voltammetric method was proposed for the determination of fenitrothion [O,O-dimethyl O-(4-nitro-m-tolyl)phosphorothioate]. The voltammetric response was evaluated in 0,04 mol l-1 Britton-Robinson buffer with respect to the accumulation time and potential, and concentration dependence. The relationship between peak current and fenitrothion concentratio...

A sensor, based on multi-wall carbon nanotubes modified glassy carbon electrode (MWCNT/GCE), was developed for determination of fenitrothion. Determining the surface area of MWCNT/GCE showed that this surface is three times more active than that of a glassy carbon electrode. The experimental parameters, such as the amount of MWCNTs, pH of the fenitrothion solution, preconcentration potential an...

Organophosphate insecticides represent one of the most widely used classes of pesticides with high potential for human exposure in both rural and residential environments. We investigated the interaction of the organophosphothioate pesticide fenitrothion (O,O-dimethyl O-(4-nitro-m-tolyl) phosphorothioate) with the human androgen receptor (AR). Fenitrothion blocked dihydrotestosterone-dependent ...

In the present study, four materials based on boron nitride nanotubes—namely pristine BNNT, C-doped tetrapeptide/BNNT, and tetrapeptide/C-doped BNNT—were examined to evaluate adsorption of organophosphorus pesticides chlorpyrifos fenitrothion. Through a quantum chemical approach molecular electronic structures, impacts C doping tetrapeptide modification nanotubes are clarified. The results reve...