BACKGROUND The prevalence of Diabetes mellitus (DM) is escalating rapidly worldwide, and associated with micro- and macrovascular complications. Diabetic neuropathy (DN) is a common complication of DM, and has a few approved therapies with limited efficacy and several side-effects. Herbal medicine is used worldwide as an effective alternative-medicine. The present study aims to investigate the ...

Seventeen daucane sesquiterpenoid esters, including a new one (4), were isolated from the root of Ferula hermonis Boiss. The structures of the isolated compounds were elucidated on the basis of spectroscopic evidence and correlated with known compounds. The relative stereochemistry of the new compound was determined using 2D NOESY and the most stable and the lowest energy conformation was deter...

Ferula persica, is the well-known species of the genus Ferula in Iran and has two varieties: persica and latisecta. They have both been extensively used in traditional medicine for a wide range of ailments. A great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. Fresh plant materials, crude extracts and isolated components of F...

The resin of Ferula gumosa (galbanum) has been used in Persia for thousands of years. The habitats of this exceptional and endemic Iranian species is closely correlated to the parameters of rainfall and, mostly, to the usual winter fog. Within the last decades, the scarcity of the raw material was the reason for a dramatic increase in adulterations. Currently, more than five times the amount ac...

The resin of Ferula gumosa (galbanum) has been used in Persia for thousands of years. The habitats of this exceptional and endemic Iranian species is closely correlated to the parameters of rainfall and, mostly, to the usual winter fog. Within the last decades, the scarcity of the raw material was the reason for a dramatic increase in adulterations. Currently, more than five times the amount ac...