Fetal anemia is a serious complication in pregnancy and associated with perinatal mortality and morbidity. During 25 years of worldwide experience with intravascular intrauterine blood transfusion, a variety of indications have been described. Intrauterine transfusion (IUT) treatment is considered most successful for fetal anemia due to red cell alloimmunization. Moreover, the use of this proce...

OBJECTIVES The expansion of pediatric-based fetal care raises questions regarding pediatric specialists' involvement in pregnancies when maternal conditions may affect pediatric outcomes. For several such conditions, we compared pediatric and obstetric specialists' attitudes regarding whether and when pediatrics consultation should be offered and their views about seeking court authorization to...

Postpartum injections of 250 ,tg of anti-D gammaglobulin prevent Rh-immunization of Rh-negative women, with an im-munosuppression success rate of approximately 95% (Eklund and Nevanlinna, 1971). The average fetomaternal transfusion, however, is less than 1-5 ml in 98% of cases (Clarke et al., 1966), and so far there are few observations on trying to suppress primary Rh-immunization due to massi...

Fetomaternal hemorrhage consists in the transmission of fetal blood cells to the mother’s bloodstream. If it is quite common in small volumes – occurring in most pregnancies – large volumes of fetomaternal hemorrhage can have serious consequences. Some risk factors are identified, but they are not always present. Decreased perception of fetal movements is the most important clinical sign, toget...

the site of the placenta. Administration ofanti-D immunoglobulin is routine after invasive procedures in Rh negative patients but is not appropriate for those already sensitised, in whom it would be ineffective.'5 In patients undergoing intra-uterine transfusions, however, fetomaternal haemorrhage may enhance maternal sensitisation. Not only might the disease be worsened in a subsequent pregnan...