Over the last decade the concept of functional foods and nutraceuticals (FFN) has gained support from various stakeholders including the food industry, scientific and academic community, government institutions or regulators, producers and consumers. However, as one begins to evaluate the global FFN industry, several issues emerge including (i) a lack of consensus across jurisdictions for ackno...

background: the differences between marginal gingiva and interdental papilla may be due to variation in the molecular composition of these two different anatomical structures. the aim of this study was to evaluate the staining intensity of fibronectin in human marginal gingiva and interdental papilla. materials and methods: in a prospective analytical study, 16 healthy subjects needing crown le...

introduction: multiple sclerosis (ms) is generally known as a manageable but not yet curable autoimmune disease affecting central nervous system. a potential therapeutic approach should possess several properties: prevent immune system from damaging the brain and spinal cord, promote differentiation of oligodendrocyte progenitor cells (opcs) into mature oligodendrocytes to produce myelin, preve...

OBJECTIVE To determine the effect of a low-lying placenta on the concentration of quantitative fetal fibronectin (qfFN) in the cervicovaginal fluid (CVF), and predictive accuracy for spontaneous preterm birth in asymptomatic high-risk women (18 + 0-24 + 0 weeks gestation). METHODS Median concentrations of qfFN were compared in women who had a low-lying placenta, covering the cervical os (n = ...

Fibronectin coating increases implant biocompatibility by enhancing surface endothelializationviaintegrin-mediated binding.

The fibronectin receptor, alpha 5 beta 1, has been shown to be required for fibronectin matrix assembly and plays an important role in cell migration on fibronectin. However, it is not clear whether other fibronectin binding integrins can take the place of alpha 5 beta 1 during matrix assembly and cell migration. To test this, we expressed the human alpha v subunit in the CHO cell line CHO-B2 t...

The major goal of this study was to determine the effect of implementing the fFN test on hospital admission rates. We hypothesized that if clinicians were using a negative fFN result to rule out preterm labor, test implementation would lead to a decrease in admissions for preterm labor. One previous study showed reduced hospital admissions for preterm labor as a result of fFN testing by compari...

background: bone marrow stromal stem cells (bmsc) are appropriate source of multipotent stem cells that are ideally suited for use in various cell-based therapies. it can be differentiated into neuronal-like cells under appropriate conditions. this study examined the effectiveness of co-stimulation of creatine and retinoic acid in increasing the differentiation of bmsc into gabaergic neuron-lik...

Charm final states in deep inelastic scattering constitute ∼ 25% of the inclusive cross-section at small x as measured at HERA. These data can reveal important information on the charm and gluon structure of the nucleon if they are interpreted in a consistent perturbative QCD framework which is valid over the entire energy range from threshold to the high energy limit. We describe in detail how...