Many group II introns encode reverse transcriptase-like proteins that potentially function in intron mobility and RNA splicing. We compared 34 intron-encoded open reading frames and four related open reading frames that are not encoded in introns. Many of these open reading frames have a reverse transcriptase-like domain, followed by an additional conserved domain X, and a Zn(2+)-finger-like re...

BACKGROUND It is well known that the C-terminal zinc-finger-3 in transcription factor Sp1 contributes more than the N-terminal zinc-finger-1 in determining Sp1's DNA binding capacity. Sp1-like artificial poly-zinc-finger proteins (ZFPs) are powerful biotechnological tools for gene-specific recognization and manipulation. It is important to understand whether the C-terminal fingers in the Sp1-li...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 introduction: health care organizations have begun applying six sigma methods into their operations. on the other hand, the difficulty of using indicators to compare health care providers in a meaningful way has led to an increased focus on using information about “adverse events”- that is , events that should not happen i...

although acrometastases are rare but clinically they are considered important. their etiology is quite different from the metastases to other sites; bronchogenic carcinoma is by far the most frequent case. the prognosis is always similar to metastatic bronchial cancer with an average survival of three months. treatment may involve distal digital amputation or antalgic radiotherapy. the main dif...

The design of a novel linkage three-phalanx finger was proposed in this paper. The finger is based on the concept of COSA (coupling and self-adaptation) and also two-phalanx COSA finger. As a combination of rigid coupled finger and self-adaptive under-actuated finger, the COSA finger has comprehensive grasping ability with human-like motion. Available topology designs were discussed in this pap...