From previous research, the ultrasonic vocalizations of male mice (Mus domesticus) to female mouse urine were hypothesized to be learned as a result of classical conditioning during adult heterosexual encounters. According to this interpretation, a previously neutral conditioned stimulus in female urine comes to elicit vocalizations as a result of its association with some other unknown uncondi...

PURPOSE The development of micturition in mice has been poorly studied because of the minute urine volume voided per micturition. We characterized development of the micturition pattern in young mice. MATERIALS AND METHODS Micturition in young and adult C57BL/6 strain mice, including 5 males and 4 females at age 3 weeks immediately after weaning, and 5 of each gender at ages 9 to 10 weeks, re...

We used protein expression profiles to develop a classification rule for the detection and prognostic assessment of bladder cancer in voided urine samples. Using the Ciphergen PBS II ProteinChip Reader, we analyzed the protein profiles of 18 pairs of samples of bladder tumor and adjacent urothelium tissue, a training set of 85 voided urine samples (32 controls and 53 bladder cancer), and a blin...

There is a need for the identification of an accurate test for the detection of recurrent bladder cancer. In this study, we evaluate the telomeric repeat amplification protocol (TRAP) assay for detection of tebomerase as a potential new method for bladder cancer detection and compare it to voided urine cytology. A urine sample and a bladder wash were obtained from 63 patients with a history of ...

Lewis X antigen in bladder cancer patients can be found in urine. In order to determine the presence of Lewis X antigen in exfoliated cells from voided urine, also cytopathologic examination and bladder ultrasound were detected in bladder cancer patients. Totally 42 patients were included in the study. Voided urine samples were obtained for immunocytology of Lewis X and cytopathology. Bladder u...

PURPOSE A recent study demonstrated improvement in nocturnal urgency in patients with overactive bladder when treated with fesoterodine. In the current study we aimed to determine which bladder diary parameters predict the response to fesoterodine in these patients. MATERIALS AND METHODS Patients with nocturnal urgency completed a 2-week, single-blind placebo run-in followed by 1:1 double-bli...

J.A. Cumming, Department of Surgery and Urology, Western General Hospital, Crewe Road, Edinburgh EH 4 2XH (UK) Dear Sir, Neutrophil elastase is released from polymorphonuc-lear leucocytes during phagocytosis, or when the cells are activated by other stimuli such as immune complexes and endotoxin [1]. Measurement of the released enzyme is thus a sensitive measure of neutrophil activity. In plasm...