NOTE: This document has been prepared for the purpose of inviting comments and suggestions on the proposals contained therein, which will then be considered by the Expert Committee on Biological Standardization (ECBS). Comments MUST be received by 14 September 2015 and should be addressed to the World Health Organization, 1211 Geneva 27, Switzerland, attention: Technologies, Standards and Norms...

The discovery of cardiolipin (Pangborn, 1941a) as the active agent in antigens for sero-reactions for syphilis enabled the production of chemically defined antigens, composed of cardiolipin, purified lecithin (Pangborn, 1941b), and cholesterol. Among the many tube and slide flocculation reactions based on the use of cardiolipin antigens, the Venereal Disease Research Laboratory (VDRL) slide flo...

Over 1.1 billion people in the world lack access to improved drinking water. Diarrhoeal and other waterborne diseases cause an estimated 1.87 million deaths per year. The Safe Water System (SWS) is a household water treatment intervention that reduces diarrhoeal disease incidence among users in developing countries. Turbid waters pose a particular challenge to implementation of SWS programmes; ...

As no published results were available of valid evaluations of common serological reactions found amongst the various racial groups of South Africa, the serological department of the Natal Pathological Service initiated a comprehensive investigation of these reactions in the racial groups of Natal. It is hoped to publish the results in a series of papers. This paper reports the results of testi...

A coagulation–microfiltration (MF) system has the potential to remove natural organic matter and mitigate membrane fouling. The effect of flocculation conditions on MF performance was investigated using three membrane modules including stirred cell, dead-end MF, and submerged MF. The experimental results were analysed in terms of filterability, particle size, and floc structure as represented b...