Objective- This research was conducted to study the effect of flunixin meglumine and ketoprofen on the healing of excisional wounding in the tendon of rats. Design- Experimental study. Animals- Twenty rats were equally divided into four groups of control, placebo (excised tendon receiving saline solution), flunixin and ketoprofen. Procedures- Right Achill complex of all groups underwent full...

JAVMA • Vol 250 • No. 2 • January 15, 2017 Flunixin meglumine is an NSAID that is approved by the FDA for the treatment of inflammatory conditions in cattle, horses, and swine and alleviation of pain associated with musculoskeletal disorders and colic in horses; it is not labeled for alleviation of pain in food-producing animals. Currently, there are no FDAapproved drugs for the treatment of py...

Objective To describe the use of therapeutic plasma exchange (TPE) in treatment flunixin meglumine overdose a cria. Case Summary A 3-day-old alpaca cria was diagnosed with ureteral obstruction and agenesis resulting severe bilateral hydronephrosis. During hospitalization, inadvertently received >65 mg/kg. Here, we report lipid emulsion TPE to mitigate toxicosis. appeared prevent any flunixin-in...

The method for quantitative determination of flunixin and its metabolite 5-hydroxyflunixin in bovine plasma has been developed and validated. Plasma samples were extracted with acetonitrile and analysed by liquid chromatography with ultraviolet detection. Extraction efficiency was tested and optimum pH conditions were established. Limit of the detection for both compounds was 0.03 μg/mL, limits...

This study explored the effects of a single administration of flunixin meglumine (acting as a non-steroidal antiinflammatory drug) and oxytetracycline combination on the reproductive performance of cows diagnosed with subclinical endometritis during the postpartum period. Cows aged 3 to 9 at 40 to 60 days postpartum were studied. Endometrial samples were collected from cows that had a uterine c...

This study was designed to evaluate the toxicity of flunixin meglumine, a nonsteroidal anti-inflammatory drug which might serve as an alternate of diclofenac that has been shown to cause toxicity in vultures. Twenty five broiler chickens of five weeks of age were randomly divided into five equal groups and treated with flunixin meglumine at the dosage rate of 0, 1.25, 2.5, 5 and 10 mg/kg body w...

FLUNIXIN MEGLUMINE Flunixin meglumine (Banamine) is frequently used in horses for the treatment of colic and endotoxemia. It has not historically been used for treating lameness, due to a perceived inferiority to phenylbutazone for musculoskeletal pain. Comparative studies in horses with naturally occurring navicular disease have shown no significant differences in the analgesic effects of flun...

The aim of this field study was to assess the impact of a single i.m. injection of lysozyme dimer and flunixin meglumine in combination with intramammary and systemic antibiotic on chemiluminescence of PMN (polymorphonuclear leucocytes) and subpopulations of lymphocyte T in blood of cows with E. coli mastitis. Examinations were performed on 30 dairy cows affected with naturally occurring acute ...

In this study, we elucidated the difference in nonsteroidal anti-inflammatory drug sensitivities between young and adult cats on therapeutic and adverse effects. In the prevention of lipopolysaccharide (LPS)-induced hyperthermia using flunixin-meglumine, young (<3 months old) and adult (>12 months old) cats of both sexes were given LPS (0.3 µg/kg, i.v.), and body temperature was measured 24 hr ...

The secretory patterns of progesterone in relation to concentrations of 15-ketodihydro-PGF(2alpha) (PGFM) during the period of luteolysis or of maternal recognition of pregnancy were determined in the blood of llamas mated either with an intact or a vasectomized male. The ability of flunixin meglumine (FM) to postpone luteolysis in non-pregnant llamas was investigated by injecting the drug intr...