Four naphthalenediimide colorimetric pH indicators were synthesized with N,N-dimethylethyleneamine at the imide positions and 5- to 7-membered heterocyclic rings bay positions, namely pyrrolidine, morpholine, piperidine azepane. The are constructed in a modular receptor–spacer–fluorophore–spacer–receptor format based on photoinduced electron transfer (PET) design. compounds studied by UV–visibl...

the affinity of low density lipoprotein (ldl) to its receptor is very important, because most of ldl-uptake pathway is done by the ldl receptor and the change in size of ldl particle and the modification in its components may affects the ldl affinity for its receptor. in this study, the effects of lipophilic agents such as vitamin e and seven volatile oils: anethol, eugenol, geraniol, limonene,...

You have accessJournal of UrologyPenile & Testicular Cancer I (MP40)1 Sep 2021MP40-05 c-MET RECEPTOR-TARGETED FLUORESCENCE ON THE ROAD TO IMAGE-GUIDED SURGERY IN PENILE SQUAMOUS CELL CARCINOMA PATIENTS Hielke de Vries, Elise Bekers, Matthias van Oosterom, Baris Karakullukcu, Henk der Poel, Fijs Leeuwen, Tessa Buckle, and Oscar Brouwer VriesHielke Vries More articles by this author , BekersElise...

The relative distribution and cellular localization of the dopamine D1 and D2 receptor subtypes were assessed in frozen sections of rat medial prefrontal cortex (mPFC). The D1 and D2 receptor binding sites were labeled with the selective high-affinity antagonists SCH 23390 and N-(p-aminophenethyl)-spiperone (NAPS), respectively, coupled to either Bodipy or Texas red fluorophores. Under the incu...

In order to better understand the cellular delivery of iron from serum transferrin (Tf), we compared iron release from receptor-bound and free Tf. While free Tf did not release all iron until below pH 4.6, receptor-bound Tf released significantly more iron at mildly acidic pH, with essentially all iron released between pH 5.6 and 6.0. Since Tf is acidified to a minimum pH of 5.4 in K562 cells, ...

Iron deficiency and heterozygous beta-thalassemia are important causes of hypochromic-microcytic anemia. Two laboratory parameters are suggested for the differentiation of such anemia. High-fluorescence reticulocyte counts and soluble transferrin receptor levels were determined in iron-deficiency anemia patients (n = 49) and heterozygous beta-thalassemia patients (n = 43). There was no signific...