نتایج جستجو برای: formulation barriers

تعداد نتایج: 191602  

Journal: :International journal of pharmaceutics 2016
Rebecca Venables Hannah Batchelor Heather Stirling John Marriott

There is a paucity of research exploring barriers to non-oral medicines administration in paediatric patients; however, these undoubtedly influence medicines adherence. Studies conducted with healthcare professionals have identified various issues with the administration and acceptance of non-oral medicines and devices (Venables et al., 2012; Walsh et al., 2015). EMA (2014) guidelines specify t...

2001
JOHN S GERO VLADIMIR KAZAKOV V. KAZAKOV

In this paper we construct an information-theoretic model of architectural drawings. This model is then used to quantify and measure the complexities and similarities of drawings. The approach is applied within a linear qualitative shape representation but can be generalized to other types of representation. The descriptive and analytic power of the proposed methods are demonstrated by studying...

Bioactive products from snail slime of “Helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. However, the poor pharmacokinetics characteristics of these natural compounds limit their use. Nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug del...

Bioactive products from snail slime of “Helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. However, the poor pharmacokinetics characteristics of these natural compounds limit their use. Nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug del...

Journal: :پژوهش و برنامه ریزی در آموزش عالی 0
سید مجید عبداللهی magid abdellahi phd student of distance education planning at the payamnoor universityدانشجوی دکتری برنامه ریزی آموزش از راه دور،دانشگاه پیام نور تهران بی بی عشرت زمانی bibi eshrat zamani psychology and education at the university of isfahanدانشکده روانشناسی و علوم تربیتی دانشگاه اصفهان عیسی ابراهیم زاده isa 1ebrahim zadeh of humanities at the university of payamnoor, tehranدانشکده علوم انسانی دانشگاه پیام نور تهران حسین زارع hossein zaree of humanities at the university of payamnoor, tehranدانشکده علوم انسانی دانشگاه پیام نور تهران بهمن زندی bahman zandi of humanities at the university of payamnoor, tehranدانشکده علوم انسانی دانشگاه پیام نور تهران

the present research identified major barriers of isfahan university teachers participation in electronic technology courses. a second goal of this study was to examine the effects of characteristics and demographics of university teachers on these barriers. in this research problems and barriers fell into three distinct categories: personal, perceptual, and contextual. a questionnaire was desi...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Kevin T Love Kerry P Mahon Christopher G Levins Kathryn A Whitehead William Querbes J Robert Dorkin June Qin William Cantley Liu Liang Qin Timothy Racie Maria Frank-Kamenetsky Ka Ning Yip Rene Alvarez Dinah W Y Sah Antonin de Fougerolles Kevin Fitzgerald Victor Koteliansky Akin Akinc Robert Langer Daniel G Anderson

Significant effort has been applied to discover and develop vehicles which can guide small interfering RNAs (siRNA) through the many barriers guarding the interior of target cells. While studies have demonstrated the potential of gene silencing in vivo, improvements in delivery efficacy are required to fulfill the broadest potential of RNA interference therapeutics. Through the combinatorial sy...

2007
Basant Lal Sharma Anna Vainchtein

We study quasistatic propagation of steps along a phase boundary in a two-dimensional lattice model of martensitic phase transitions. For analytical simplicity, the formulation is restricted to antiplane shear deformation of a cubic lattice with bi-stable interactions along one component of shear strain and harmonic interactions along the other. Energy landscapes connecting equilibrium configur...

Journal: :Ergonomics 2004
Karim Abdel-Malek Jingzhou Yang Richard Brand Emad Tanbour

Significant attention in recent years has been given towards obtaining a better understanding of human joint ranges, measurement, and functionality, especially in conjunction with commands issued by the central nervous system. Studies of those commands often include computer algorithms to describe path trajectories. These are typically in "open-form" with specific descriptions of motions, but n...

Journal: :I. J. Robotics and Automation 2005
Jingzhou Yang Karim Abdel-Malek Kyle Nebel

This paper presents a rigorous mathematical formulation for modelling the upper extremity that is capable of considering a relatively large number of degrees of freedom, thus yielding a realistic model and associated envelope. Kinematic models are used to determine the reach envelope in closed form and to better understand human motion. Joint ranges of motion are taken into account by transform...

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