Abstract. The Fokker-Planck equation (FPE) approximation is applied to a subspace of the state space of the chemical master equation (CME). The CME-FPE-hybrid method exploits the lower cost of the FPE approximation compared to the full CME. A fourth order finite difference approximation of the FPE part of the hybrid is described and demonstrated on a biologically relevant model in five dimensions.

This paper concerns the asymptotic properties of a class of criteria for model selection in linear regression models, which covers the most well known criteria as e.g. MALLOWS' Cp, CV (cross-validation), GCV ( generalized cross-validation), AKAIKE's AIC and FPE as well as SCHWARZ' BIC. These criteria are shown to be consistent in the sense of selecting the true or larger models, assuming i.i.d....

We conducted a non-randomized retrospective study of the treatment locally advanced head and neck squamous-cell carcinoma (LA-SCCHN), comparing induction chemotherapy (ICT) with cetuximab plus cisplatin fluorouracil (FPE) docetaxel (TPF), followed by radiotherapy cetuximab. non-randomly assigned 24 patients (all whom had N stage N2 or N3 no distant metastases were candidates for organ preservat...

CONTEXT Our previous studies showed that porcine pancreatic enzymes in Syrian golden hamsters with peripheral insulin resistance normalizes the plasma insulin level, reduces the size of enlarged islets and inhibits the increased DNA synthesis in the beta-cell of islets. OBJECTIVE In order to exclude the possibility that these effects was attributed to some contaminants of this crude material,...

A novel free piston expander-linear generator (FPE-LG) integrated unit was proposed to recover waste heat efficiently from vehicle engine. This integrated unit can be used in a small-scale Organic Rankine Cycle (ORC) system and can directly convert the thermodynamic energy of working fluid into electric energy. The conceptual design of the free piston expander (FPE) was introduced and discussed...

Biological thin films may form on a surface by specific molecular interactions. The fixed polarizer ellipsometer (FPE) is a sensitive instrument that detects biological thin films either qualitatively or quantitatively. The design is simple and inexpensive. The assays are formatted on an optical surface, and the FPE detection is based on the phase shift of linearly polarized light after reflect...

We examined 1,092 skulls of captive and free-living individuals, representing 33 felid species, to determine the prevalence of focal palatine erosion (FPE). FPE was detected in 3.2% of cats evaluated, including cheetah (Acinonyx jubatus) and 14 other felid species. The prevalence of FPE between cheetah (9.4%; n = 64) and non-cheetah species (2.8%; n = 1,028) (χ(2) test; P = 0.004) and between c...

murine and rat models of vascular endothelial growth factor depletion leading to endotheliosis, alpha-3 chain of collagen IV knock-out mouse, that represents a murine model of autosomal recessive Alport syndrome, Masugi nephritis model in rats, rare patients with a familial form of nephrotic syndrome in whom podocytes are fully preserved, even in the occurrence of heavy proteinuria, women with ...

murine and rat models of vascular endothelial growth factor depletion leading to endotheliosis, alpha-3 chain of collagen IV knock-out mouse, that represents a murine model of autosomal recessive Alport syndrome, Masugi nephritis model in rats, rare patients with a familial form of nephrotic syndrome in whom podocytes are fully preserved, even in the occurrence of heavy proteinuria, women with ...

murine and rat models of vascular endothelial growth factor depletion leading to endotheliosis, alpha-3 chain of collagen IV knock-out mouse, that represents a murine model of autosomal recessive Alport syndrome, Masugi nephritis model in rats, rare patients with a familial form of nephrotic syndrome in whom podocytes are fully preserved, even in the occurrence of heavy proteinuria, women with ...