The number of requests for testosterone testing in adult males has been increasing in recent years. In this review, the biochemistry and physiology of testosterone in males relevant to the chemical pathologist or clinical biochemist is outlined. The methodology for total testosterone and various laboratory tests associated with the assessment of testosterone status including free testosterone, ...

OBJECTIVE To evaluate the association between androstenedione, testosterone, and free testosterone and metabolic disturbances in polycystic ovary syndrome. METHODS We analyzed the association between androstenedione, testosterone, and free testosterone and metabolic parameters in a cross-sectional study including 706 polycystic ovary syndrome and 140 BMI-matched healthy women. Polycystic ovar...

AIMS High androgen levels are presumed by many to explain the male predisposition to coronary artery disease. However, natural androgens inhibit male atherosclerosis(1). Our aim was to determine whether levels of androgens differ between men with and without coronary artery disease. METHODS AND RESULTS Ninety male subjects (60 with positive, and 30 with negative coronary angiograms) were recr...

Background: Preeclampsia along with its complications seems to be one of the major causes of maternal morbidity and mortality. Despite numerous studies, the pathology of preeclampsia has not yet been fully elucidated. This study, therefore, determines whether maternal serum levels of androgen and progesterone are higher in patients with preeclampsia than in matched control subjects. Methods: Se...

OBJECTIVES There are technical limitations for the currently available methods of measuring serum total and free testosterone in females. The study objectives were to evaluate the usefulness of serum total testosterone, sex hormone-binding globulin (SHBG), free androgen index (FAI), and calculated free testosterone (CFT) in the assessment of androgen status in women investigated for suspected h...

introduction: this research was aimed at examining acute responses of hormones such as growth hormone (gh), total testosterone (tt), free testosterone (ft), free fatty acid (ffa) and cortisol to resistance (r), endurance (e) and endurance-resistance (er) exercise. methods: the participants of this study were 10 healthy young men. r protocol included bench press, lateral pull down, leg extension...

objectives: this study designed to detect the prevalence of ovarian and/or adrenal hyperandrogenism in women with polycystic ovary syndrome (pcos).materials: one hundred pcos women included in this cross sectional study after informed consent and approval of the study by local institute ethical committee. diagnosis of pcos based on the rotterdam eshre criteria. studied women underwent complete ...

The role of testosterone on the development of hypertension is controversial, especially in women with polycystic ovary syndrome (PCOS) who have higher prevalence of obesity and insulin resistance than women without PCOS. Little is known about the association between serum testosterone level and blood pressure in young women with PCOS. In the 151 young Taiwanese women with PCOS enrolled in this...

OBJECTIVES To To compare testosterone undecanoate versus propionyl-L-carnitine plus acetyl-L-carnitine and placebo in the treatment of male aging symptoms. METHODS A total of 120 patients were randomized into three groups. The mean patient age was 66 years (range 60 to 74). Group 1 was given testosterone undecanoate 160 mg/day, the second group was given propionyl-L-carnitine 2 g/day plus ace...

Background: Women suffer more often from depression than men. Social research suggests that high androgen levels cause aggressive behavior in men and women, and consequently cause depression. The purpose of this study was to determine serum levels of androgens, especially testosterone, in patients with depression. Material and methods: In this case-controlled study, we measured serum testoste...