Altered regulation of 5-HT1A receptors is implicated in mood disorders such as anxiety and major depression. To provide insight into its transcriptional regulation, we previously identified a novel DNA element [14 bp 5'-repressor element (FRE)] of the 5-HT1A receptor gene that mediates repression in neuronal and non-neuronal cells (Ou et al., 2000). We have now cloned a novel DNA binding protei...

The effect of stress on the mRNA and protein level of the 5-HT1A receptor and two of its key transcriptional modulators, NUDR and Freud-1, was examined in the prefrontal cortex (PFC) and hippocampus (Hp) using rodent models: olfactory bulbectomy (OB) and prenatal stress (PS) in male and female rats; chronic mild stress in male rats (CMS) and pregnancy stress. In PFC, CMS induced the most widesp...

A Well-Deserved Sabbath Rest: Three Freud Patriarchs Benjamin Goodnick, PH.D* The Talmud relates that King David constantly occupied himself with study on the Sabbath, for he had been foretold that on that day of the week he would die (Bab. Talmud, Shabbat 30a). Indeed, it was only when he ceased his study one Sabbath that the Angel of Death was able to claim him. In a related sense, we can spe...

Julen Hernandez Lallement, Katarina Kuss, Peter Trautner, Bernd Weber, Armin Falk, and Klaus Fliessbach Center for Economics and Neuroscience, University of Bonn, Nachtigallenweg, 53113 Bonn, Germany, Department of Comparative Psychology, Institute of Experimental Psychology, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany, Department of Epileptology, University Hospital Bonn, S...

Among Freud's papers, we find instances in which Freud describes the "psychopathology of everyday life" as he found it in himself and in others. "A Religious Experience" (Freud, 1928) contains examples of both kinds. In addition, this paper contains a slip of which Freud appears to have been unaware. Freud's paper interprets a religious conversion described in a letter written to him in English...

An alternative subtitle to this essay, which my non-Freudian Minnesota colleagues urged upon me, would have been, "Whose mind does the mindreader read?" To motivate discussion of a topic not deemed important by some today, consider the story of the last "Congress" between Freud and Fliess, the rupture of their relationship at Achensee in the summer of 1900—the last time the two men ever met, al...

In undergoing this life, many people always try to do and get the best. New knowledge, experience, lesson, and everything that can improve the life will be done. However, many people sometimes feel confused to get those things. Feeling the limited of experience and sources to be better is one of the lacks to own. However, there is a very simple thing that can be done. This is what your teacher ...