نتایج جستجو برای: frmd5

تعداد نتایج: 11  

2017
Astrid Yeo Li Li Liling Warren Jennifer Aponte Dana Fraser Karen King Kelley Johansson Allison Barnes Colin MacPhee Richard Davies Stephanie Chissoe Elizabeth Tarka Michelle L O'Donoghue Harvey D White Lars Wallentin Dawn Waterworth

Darapladib, a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, failed to demonstrate efficacy for the primary endpoints in two large phase III cardiovascular outcomes trials, one in stable coronary heart disease patients (STABILITY) and one in acute coronary syndrome (SOLID-TIMI 52). No major safety signals were observed but tolerability issues of diarrhea and odor were common (up t...

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