The life cycle of calicivirus is not fully understood because most of the viruses cannot be propagated in tissue culture cells. We studied the mechanism of calicivirus entry into cells using feline calicivirus (FCV), a cultivable calicivirus. From the cDNA library of Crandell-Rees feline kidney (CRFK) cells, feline junctional adhesion molecule 1 (JAM-1), an immunoglobulin-like protein present i...

Suppose we are given a solid of revolution generated by a conic section. Slice out a frustum of the solid [14, diagrams pp. 77, 80]. Then, construct a cylinder, with the same height as the frustum, whose diameter coincides with the diameter of the frustum at the midpoint of its height. What is the difference between the volume of the frustum and the volume of this cylinder? Does this difference...

Feline calicivirus (FCV) is a highly contagious pathogen of cats that can be grown in cultured cells. FCV is used as a model to study nonculturable caliciviruses, such as noroviruses. We determined the complete genome sequence of the FCV 2280 strain from the American Tissue Culture Collection.

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemi...

SUMMARY This Report considers theoretically and experimentally some of the problems associated with the flexure of two unequal cylindrical shells Joined by a conical frustum. Particular attention is given to the determination of the overall flexursl stiffness of the conical frustum and to structural design considerations associated with the provision of a separation capability in the frustum. T...

We have prepared monoclonal antibodies to the capsid protein of feline calicivirus (FCV). These antibodies are directed against two close but distinct epitopes, only one of which is involved in virus neutralization. We have used these antibodies and immune cat serum in immunoprecipitation and Western blotting experiments and have identified novel proteins in FCV-infected cells which we term P78...

Famciclovir (FCV) is efficacious in the treatment of acute herpes zoster and recurrent genital infections but has not been used to treat ocular herpes simplex virus (HSV) infections. We evaluated the efficacy of orally administered FCV in treating HSV-1 epithelial keratitis and determined its effects on the establishment of latency and subsequent reactivation. Rabbits were inoculated with HSV-1...

During the past decade, several outbreaks of severe systemic disease associated with Feline calicivirus (FCV) have occurred in the USA and the UK. This new disease has caused high mortality in the affected animals and has been termed virulent systemic (VS)-FCV disease. Currently, there are no genetic or in vitro diagnostic methods to distinguish viruses isolated from cases of VS-FCV disease fro...

The issue of screen size is discussed with respect to the task of navigating in 3D computer graphics environments. Two variables are isolated, the observer’s visual field of view (observer VA) subtended by a screen, and the viewing frustum angle (frustum VA) determined by the computer graphics geometry. It is possible to have these set to be identical, which according to one hypothesis should l...