Introduction: Headache is one of the essential symptoms pituitary adenoma associated with tumor and patient’s characteristics. The pattern adenoma-related headaches varies widely can significantly impact quality life. Objectives: We aimed to investigate severity in patients Iran. Patients Methods: In this cross-sectional study, we investigated 109 an initial complement headaches. diagnosis was ...

purpose: to study early treatment outcomes and complications of gamma knife radiosurgery (gkrs) in patients with functional and nonfunctional adenomas. methods: one hundred patients with a pituitary adenoma who were treated between 2011 and 2014 at iran gamma knife center were studied. the patients were followed up at least 2 years. radiosurgery was performed using the leksell gamma unit. the m...

The aim of the current study was to investigate the pathogenesis of pituitary adenoma through screening of the differentially-expressed genes (DEGs) and proteins in normal pituitary and pituitary adenoma tissues, and analyzing the interactions among them. Following the acquisition of gene expression profiling data from a public functional genomics data repository, Gene Expression Omnibus, DEGs ...

The classification of pituitary tumors is frequently updated to optimize guidance for clinical treatment based on current knowledge. To date, the World Health Organization conducts periodic expert review consensus meetings and publishes results. These include recommendations behavior more aggressive, high Ki-67 index (>3%)pituitary. A Knosp grade (>3) associated with a risk recurrence. We repor...

Introduction. Familial hypocalciuric hypercalcemia is a rare inherited calcium metabolism disorder in which an alteration of the parathyroid hormone secretion set-point causes with relative hypocalciuria. Some data suggest that its prevalence around 74.1 per 100,000 inhabitants. Often, patients are asymptomatic. However, they can develop mild symptoms and overactive adenoma, main differential d...

The potent growth-promoting activity of insulin-like growth factor-II (IGF-II) is highly regulated during development but frequently up-regulated in tumors. Increased expression of the normally monoallelic (paternally expressed) mouse (Igf2) and human (IGF2) genes modify progression of intestinal adenoma in the Apc(Min/+) mouse and correlate with a high relative risk of human colorectal cancer ...