We determined the susceptibilities of five strains of Trichomonas vaginalis, one of which was metronidazole resistant, to 50 antimicrobial agents. For the metronidazole-susceptible strains, the most active agents were metronidazole, tinidazole, mebendazole, furazolidone, and anisomycin. Against the resistant strain mebendazole, furazolidone, and anisomycin were the most active. Antifungal agent...

BACKGROUND Increasing resistance to clarithromycin and nitroimidazole is the main cause of failure in the Helicobacter pylori eradication. The ideal retreatment regimen remains unclear, especially in developing countries, where the infection presents high prevalence and resistance to antibiotics. The study aimed at determining the efficacy, compliance and adverse effects of a regimen that inclu...

Background: Helicobacter pylori infection is a common chronic human bacterial infection. Tripletherapy regimen containing a proton pump inhibitor, clarithromycin, and either amoxicillin or metronidazole is commonly used as first-line treatment for its eradication. However, it may not provide the acceptable eradication rate. The present study was designed to evaluated efficacy of low dose furazo...

Overall, 525 (55%), 420 (44%), 944 (99%), 948 (100%), and no strains from Dhaka and 186 (54%), 165 (48%), 332 (97%), 343 (100%), and no strains from Matlab were resistant to tetracycline, erythromycin, trimethoprim-sulphamethoxazole, furazolidone, and ciprofloxacin respectively. Prior to October 2004, most strains were resistant to trimethoprim-sulphamethoxazole and furazolidone but were unifor...

Metronidazole and furazolidone were compared for efficacy in 268 seven to 11 year old children infected with giardiasis. With metronidazole the cure rate was 82.3% and 80.0% in boys and girls respectively, while furazolidone showed an efficacy of74.4% and 71. 7% in the corresponding groups. The overall efficacy was 81.1 % with metronidazole and 73.3% with furazolidone. There were no signif...

BACKGROUND Furazolidone has been used as an alternative for clarithromycin or metronidazole in Helicobacterpylori (H.pylori) eradication regimens. In Iran, 14-day Furazolidone-containing quadruple regimens have shown promising eradication rates, but short-course, low dose therapies are always attractive. Therefore, we designed a study to compare the efficacy of two 10-day triple regimens contai...

We read with great interest the article published by Hosseini et al.1 in October issue of Middle East Journal of Digestive Diseases. Briefly, in this article, authors concluded that furazolidone based therapeutic regimens (in moderate and even high-dose) were not preferable for first-line treatment against H.pylori infection among the northern population in Iran.1 Altogether, some points we fou...

Pigs had a higher degree of gastrointestinal protozoa infection 93 out of 100 faecal samples. Balantidium coli rd infected pigs were controlled effectively by oxytetracycline (100% on 3 day of observation) and Metronidazole th +Furazolidone combination (100% on 5 day of observation). Initially B. coli infected pigs had decreased haemoglobin, pack cell volume and total erythrocyte count values, ...

A Bacillus stearothermophilus var. calidolactis C953 tube test was evaluated for its ability in detecting the residue of selected anticoccidial drugs in poultry, specially sulfamethazine, furazolidone, and amprolium. Various concentrations of each drug were injected into chicken liver and kidney tissues and these tissues were tested to determine the drug detection limits for each drug. The dete...

Furazolidone in concentrations which had little effect on the growth of host organisms greatly reduced the yield of phage phi149 from the host Vibrio cholerae OGAWA 154. This phage was resistant to the in vitro action of the drug. The phage yield of infected bacteria depended significantly on the time of addition or withdrawal of the drug. The average burst size of the drug-treated and infected...