Chinese medicine plays an important role in providing medical care for people in countries with large Chinese communities, including Hong Kong. The aconite herb is one of the commonly-prescribed ingredients for various clinical problems. However, due to its narrow therapeutic index, toxicities are not uncommonly encountered, including life-threatening cardiac arrhythmias like ventricular arrhyt...

Hypaconitine (HA) and glycyrrhetinic acid (GA) are active components of Fuzi (Aconitum carmichaelii) and Gancao (Glycyrrhiza uralensis Fisch); they have been used in compatibility for chronic heart failure (CHF) from ancient times. The purpose of the present research was to explore whether apoptosis pathways were related with the protective effects of HA + GA against CHF rats or not. The rats w...

Current antidepressants are clinically effective only after several weeks of administration. We show that Fuzi polysaccharide-1 (FPS), a new water-soluble polysaccharide isolated from Fuzi, which has been used to treat mood disorders in traditional Chinese medicine for centuries, increases the number of newborn cells in the dentate gyrus in adult mice, and most of these cells subsequently diffe...

BACKGROUND Shen-Fu decoction is a traditional Chinese medicine prescription with a 3:2 ratio of Radix Ginseng and Fuzi (Radix Aconiti lateralis praeparata). Ginsenosides and alkaloids are considered to be the main active components of Shen-Fu decoction. However, no analytical methods have been used to quantitatively analyse both components in Shen-Fu decoction simultaneously. RESULTS We succe...

Abstract By rejoining several fragmentary slips in the Shanghai Museum * Shi Liu wen yu Fuzi manuscript, this article seeks to adjust order of existing bamboo as well clarify meaning text. On basis, and through a comparison with transmitted texts, identities main characters “Shi Liu” “Master” manuscript are discussed. We find that words, deeds, thoughts bear certain similarities Qiu” “Confucius...

The differentiation of parasitic and saprophytic leptospirae may be of importance not only from a taxonomical point of view, but it can present a diagnostic problem in culturing strains from different materials, even from human specimens (Fuzi and Cs6ka, Zentr. Bakteriol. Parasitenk., Abt. I, Orig., 178, 222, 1960). The determination of pathogenicity for laboratory animals cannot be regarded as...

the chemical components in the decoctions of chinese herbal medicines are not always the same as those in the crude herbs because of the insolubility or instability of some compounds. in this work, a high-performance liquid chromatography (hplc) coupled with electrospray ionization (esi) tandem mass spectrometry method was developed to explore dynamic variation patterns of aconitum alkaloids in...