نتایج جستجو برای: g13 pi

تعداد نتایج: 44731  

Journal: :Molecular pharmacology 2006
Li Zhang Cherisse DiLizio David Kim Emer M Smyth David R Manning

Despite advances in the understanding of pathways regulated by the G12 family of heterotrimeric G proteins, much regarding the engagement of this family by receptors remains unclear. We explore here, using the thromboxane A2 receptor TPalpha, the ability of G12 and G13 to report differences in the potency and efficacy of receptor ligands. We were interested especially in the potential of the is...

2013
Wimolpak Sriwai Sunila Mahavadi Othman Al-Shboul John R. Grider Karnam S. Murthy

We examined expression of protease-activated receptors 2 (PAR2) and characterized their signaling pathways in rabbit gastric muscle cells. The PAR2 activating peptide SLIGRL (PAR2-AP) stimulated Gq, G13, Gi1, PI hydrolysis, and Rho kinase activity, and inhibited cAMP formation. Stimulation of PI hydrolysis was partly inhibited in cells expressing PAR2 siRNA, Gaq or Gai minigene and in cells tre...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه کاشان - دانشکده ریاضی 1390

شاخص توپولوژیک عددی حقیقی است که به یک گراف نسبت داده می شود و تحت یک ریختی گراف ثابت می ماند. شاخص های توپولوژیک برای بررسی خواص فیزیکی-شیمیایی ترکیبات شیمیایی به کار می روند. شاخص ‎ pi ‎ در مقاله ای در سال ‎2009‎ در تلاش جهت یافتن رابطه ای دقیق برای محاسبه ی شاخص ‎ pi ‎ رأسی حاصل ضرب دکارتی گراف ها معرفی شد. بعدها کاربردهای فراوانی از این شاخص در علوم نانو و شیمی به دست آمد. مطالعه ی ریاضی ای...

Journal: :Archives of Disease in Childhood 2013

Journal: :international journal of industrial mathematics 2014
a. arjomandfar o. khormali

in this paper, at first we mention to some results related to pi and vertex co-pi indices and then we introduce the edge versions of co-pi indices. then, we obtain some properties about these new indices.

Journal: :iranian journal of mathematical chemistry 2015
a. maden e. kaya

in this paper, we present some inequalities for the co-pi index involving the some topological indices, the number of vertices and edges, and the maximum degree. after that, we give a result for trees. in addition, we give some inequalities for the largest eigenvalue of the co-pi matrix of g.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Julie Quoyer Jay M Janz Jiansong Luo Yong Ren Sylvain Armando Viktoria Lukashova Jeffrey L Benovic Kenneth E Carlson Stephen W Hunt Michel Bouvier

Short lipidated peptide sequences derived from various intracellular loop regions of G protein-coupled receptors (GPCRs) are named pepducins and act as allosteric modulators of a number of GPCRs. Recently, a pepducin selectively targeting the C-X-C chemokine receptor type 4 (CXCR4) was found to be an allosteric agonist, active in both cell-based assays and in vivo. However, the precise mechanis...

Journal: :International journal of statistics and applied mathematics 2023

Breeding for novel genotypes with high yield and stability is a crucial objective in agriculture. Environmental factors play significant role determining genotype's response, which commonly known as genotype-by-environment interaction. In this study, multi-environment experiment three replications of twenty-nine pearl millet one year (2019) was conducted at eight locations India. The Additive m...

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