BACKGROUND Breast cancer is the most frequently diagnosed malignancy among Chilean women and an increasingly significant public health threat. This study assessed the accuracy of breast cancer risk perception among underserved, Chilean women. METHODS Women aged 50 to 70 years, with no mammogram during the last 2 years, were randomly selected from a community clinic registry in Santiago, Chile...

The Wada Test (WT) is part of the presurgical evaluation for refractory epilepsy. The WT is not standardized and the protocols differ in important ways, including stimulus type of material presented for memory testing, timing of presentations and methods of assessment. The aim of this study was to contribute to establish parameters for a WT to Brazilian population investigating the performance ...

Background: Prediction of breast cancer risk and identifying women who are at high risk of breast cancer, would be a great help for planning and conducting screening programs. The aim of this study was to estimate the 5-year breast cancer risk among women in Isfahan. Methods: This cross-sectional study was conducted on 9674 women aged 35-69 years who referred to the Breast Cancer Screening Cen...

Gail Wilkes, RNC, MS, AOCN®, is an oncology nurse educator at Boston Medical Center in Massachusetts. Wilkes is a member of the speaker’s bureau for Sanofi-Synthelabo, Inc., the manufacturer of oxaliplatin (EloxatinTM). (Mention of specific products and opinions related to those products do not indicate or imply endorsement by the Clinical Journal of Oncology Nursing or the Oncology Nursing Soc...

In a Perspective, Linda-Gail Bekker and Glenda Gray discuss HIV vaccine development.

Background: Breast cancer is one of the most important malignancies in both developed and developing countries. Objectives: To reduce the burden of this disease, the prediction of individuals at risk and implementation of efficient preventive interventions can be effective. The present study was aimed at investigating five-year and lifetime risks of the breast cancer in a rural community in Za...

There is an increasing need for accurate prediction methods of assessing individual risk for breast cancer for both clinical and research purposes. The purpose of this study is to compare the Gail and Claus model risk estimates of breast cancer among women with a family history of breast cancer. This study presents risk estimates from two models of breast cancer risk in 491 women 18 to 74 years...

PURPOSE The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. METHODS We validated the modified Gail model (model 2), Asian American Gail m...

BACKGROUND The Gail model is a validated breast cancer risk assessment tool that is primarily based on nonmodifiable breast cancer risk factors. Conversely, mammographic breast density is strongly correlated with breast cancer risk and responds to risk-modifying interventions. The purpose of our study was to correlate mammographic density with breast cancer risk as calculated by the Gail model ...

BACKGROUND Recent guidelines suggest that chemoprevention with tamoxifen may be appropriate for women who have a 5-year risk of breast cancer greater than 1.66% calculated using the Gail model. OBJECTIVES To determine whether nipple aspirate fluid (NAF) cytology combined with the Gail model provides breast cancer risk assessment that is superior to either method alone. METHODS Prospective o...