Aim To comparatively evaluate the efficacy of disinfecting ability of garlic oil, neem oil, clove oil, and tulsi oil with autoclaving on endodontic K files tested against Enterococcus faecalis. Materials and methods Fifty endodontic K files were exposed to the test micro-organism and checked for its disinfecting ability using three different methods. Result Garlic oil, clove oil, tulsi oil ...

Multiple blood cell types and metabolic pathways involved in the modulation of platelet reactivity were investigated in streptozotocin-induced diabetic rats treated with garlic oil. Platelet counts of diabetic rats treated with garlic oil were significantly (P<0.01) reduced as compared to diabetic control rats. Garlic oil also increased the leucocyte counts of diabetic rats as compared to diabe...

BACKGROUND Corrosive esophageal burns, particularly common in developing countries, lead to different problems in different age groups. The ingestion of corrosive substances can cause such problems as stricture of the esophagus, to acute perforation, and even death. Because stricture formation is related to the severity of the initial injury, the prevention of stricture constitutes a main goal ...

Stavudine (Zerit, d4T) is widely used as an anti HIV infection drug. It prevents HIV by altering the genetic material of healthy cells but causes mutations in mitochondrial and nuclear DNA. It also produces clastogenic effects in mice. In the present investigation, comet assay test was applied to evaluate the possible genomic damage caused by stavudine and also the ameliorating effects of garli...

BACKGROUND Since long high fat diet (HFD) is being blamed for causing fatty degeneration of liver and formation of atheromatous plaques. At present, no proper pharmacotherapy is available for both the conditions. In this study, different substances containing monounsaturated fatty acids were used to observe their protective effects in the HFD induced damage to liver and coronary vessels. OBJE...

Tuberculosis is one of the major public health problems faced globally. Resistance of Mycobacterium tuberculosis to antitubercular agents has called for an urgent need to investigate newer drugs to combat tuberculosis. Garlic (Allium sativum) is an edible plant which has generated a lot of curiosity throughout human history as a medicinal plant. Garlic contains sulfur compounds like allicin, aj...

We investigated the effects of garlic oil and diallyl disulfide (DADS) on glycemic control and renal function in rats with streptozotocin-induced diabetes. Rats received by gavage garlic oil (100 mg/kg body wt) or DADS (40 or 80 mg/kg body wt) every other day until 16 weeks after the induction of diabetes. The control rats were treated with corn oil only. Neither garlic oil nor DADS significant...

INTRODUCTION: The activity of garlic oil extract against Schistosoma japonicum cercariae was evaluated. METHODS: The in vitro and in vivo cercaricidal activities against S. japonicum larvae were determined. RESULTS: Exposure to ≥ 10-6 (v/v) garlic emulsions for 30 min led to 100% cercariae mortality; pre-exposure treatment with ≥ 10-4 (v/v) garlic emulsions showed 100% preventive efficacy ...

We analyzed the protective effect of garlic oil on hepatic and blood lipid peroxidation and the antioxidant status during buccal pouch carcinogenesis induced by 7,12dimethylbenz[a]anthracene (DMBA) in male Syrian hamsters. Enhanced lipid peroxidation in the liver and blood of tumor-bearing animals was accompanied by a significant decrease in antioxidant levels. Topical application of garlic oil...

Capsicum and garlic were extracted in xylene. The obtained extracts were used to prepare four emulsifable concentrates "EC's". Formula A "capsicum xylene extract + emulsifier", Formula B "garlic xylene extract + emulsifier", Formula C "capsicum xylene extract in boiled linseed oil + emulsifier" and Formula D "garlic xylene extract in boiled linseed oil + emulsifier ". All prepared formulations ...