Gas gangrene, clostridial myonecrosis, is one of the most serious infectious diseases, characterized by rapidly progressive destruction of deep soft tissues and production of gas within the tissues. We presented a case of fatal spontaneous gas gangrene due to Clostridium perfringens in a patient with acute lymphoblastic leukemia during remission induction chemotherapy phase.

Gas gangrene is a necrotic infection of soft tissue associated with high mortality, often necessitating amputation in order to control the infection. Herein we present a case of gas gangrene of the arm in an intravenous drug user with a history of intramuscular injections with normal saline in the shoulder used to provoke pain for recovery after drug induced coma. The patient was early treated ...

INTRODUCTION Pneumatosis coli is a rare disease with heterogeneous symptoms which can be detected in the course of various acute and chronic intestinal diseases in children, such as necrotizing enterocolitis, intestinal obstruction and intestinal bacteriological infections. CASE PRESENTATION We report the case of a 12-month-old boy who died of pneumatosis coli caused by an acute intestinal ga...

BACKGROUND Today, gas gangrene is rare, but still many of the patients die, despite having received timely treatment. CASE PRESENTATION This report highlights the cases of three different patients, who were transferred to our surgical department in 2006. The first patient (Patient_A), with the suspected diagnosis "femoral hematoma", a second patient (Patient_B) because of an "acute abdomen" a...

Clostridium perfringens is a common cause of the fatal disease gas gangrene (myonecrosis). Established gas gangrene is notable for a profound absence of neutrophils and monocytic cells (phagocytes), and it has been suggested that the bactericidal activities of these cells play an insignificant role in controlling the progression of the infection. However, large inocula of bacteria are needed to...

Introduction The term necrotising fasciitis (NF) was first coined in 1952 by Wilson1 to describe a rapidly progressive inflammation and necrosis of subcutaneous tissues and the deep layer of superficial fascia with sparing of the deep fascia and muscle. It had previously been described variously as haemolytic gangrene, acute streptococcal gangrene, gangrenous erysipelas, necrotising erysipelas,...