One of the fundamental problems in computational biology identification of genes in very long genome sequences. As we know DNA is a sequence of nucleotide molecules, or bases, which encode instructions for generation of proteins. However, not all of these bases correspond directly to amino acids. Even within a gene, a relatively small percentage of the nucleotides might actually be translated i...

Growing amount of information on biological sequences has made application of statistical approaches necessary for modeling and estimation of their functions. In this paper, sensitivity and specificity of the first and second Markov chains for prediction of genes was evaluated using the complete double stranded  DNA virus. There were two approaches for prediction of each Markov Model parameter,...