Background: Deregulation of FOXO3a gene which belongs to Forkhead box O (FOXO) transcription factors, can cause cancer (e.g. breast cancer). FOXO factors have important role in ubiquitination, acetylation, de-acetylation, protein-protein interactions and phosphorylation. Understanding the regulation and mechanisms of FOXO3a can lead to cancer treatment. The aim of this study recent association...

background: polycystic ovary syndrome (pcos) is a complex disease having both genetic and environmental components and candidate genes on obesity and insulin metabolism have been hypothesized to be involved in its etiology. objective: we examined the possible association of adiponectin and insulin receptor gene polymorphisms with pcos. materials and methods: a total of 186 women with pcos using...

Proper scheduling of tasks leads to optimum using of time and resources, in order to obtaining best result. One of the most important and complicated scheduling problems is open shop scheduling problem. There are n jobs in open shop scheduling problem which should be processed by m machines. Purpose of scheduling open shop problem is attaining to a suitable order of processing jobs by specified...

Evolutionary algorithms incorporate principles from biological population genetics to perform search, optimization, and learning. This article discusses issues arising in the application of evolutionary algorithms to problems in robotics.

The effect of landscape patterns and environmental factors on the population structure genetic diversity organisms is well-documented. However, this still unclear in case Mymaridae parasitoids. Despite recent advances machine learning methods for genetics, ensemble needs further investigation. Here, we evaluated performance different boosting algorithms analyzed effects variations tea green lea...

Proper scheduling of tasks leads to optimum using of time and resources, in order to obtaining best result. One of the most important and complicated scheduling problems is open shop scheduling problem. There are n jobs in open shop scheduling problem which should be processed by m machines. Purpose of scheduling open shop problem is attaining to a suitable order of processing jobs by specified...

 This paper present unequal-sized facilities layout solutions generated by a genetic search program named LADEGA (Layout Design using a Genetic Algorithm). The generalized quadratic assignment problem requiring pre-determined distance and material flow matrices as the input data and the continuous plane model employing a dynamic distance measure and a material flow matrix are discussed. Computa...

The WHO classification of soft tissue tumours categorizes the lesions based on histological differentiation. In recent fifth edition (2020), many new entities have been introduced, their distinct biological behaviour, genetics and morphology. With advances better understanding molecular genetics, several novel recurrent genetic alterations incorporated in this edition. These may serve as reliab...