Triple negative breast cancer (TNBC) is a group of cancers whose heterogeneity and shortage of effective drug therapies has prompted efforts to divide these cancers into molecular subtypes. Our computational platform, entitled GenEx-TNBC, applies concepts in systems biology and polypharmacology to prioritize thousands of approved and experimental drugs for therapeutic potential against each mol...

In Open Innovation, companies open up their innovation activities to external stakeholders. Using web-based ideation platforms (WBIP), companies crowdsource ideas for innovations from their customers. Ideation can be considered as a create process. Therefore, in this research we analyze how current web-based ideation platforms run by firms support Shneiderman’s GENEX framework that aims at supp...

In Open Innovation, companies open up their innovation activities to external stakeholders. Using web-based ideation platforms (WBIP), companies crowdsource ideas for innovations from their customers. Ideation can be considered as a create process. Therefore, in this research we analyze how current web-based ideation platforms run by firms support Shneiderman’s GENEX framework that aims at supp...

To the editor: The paper by Friesenbichler and colleagues [2] reported the findings of a truncated clinical study involving 31 patients treated for bone tumors by curettage, and filling of the defect using geneX (Biocomposites Ltd., Staffordshire, UK). ‘‘The reconstructive approach after intralesional curettage is controversial and clinical practice varies,’’ the authors reported. ‘‘Polymethylm...

A challenge for human-computer interaction researchers and user interface designers is to construct information technologies that support creativity. This ambitious goal can be attained by building on an adequate understanding of creative processes. This paper offers the four-phase genex framework for generating excellence: Collect: learn from previous works stored in digital libraries Relate: ...