BACKGROUND Recombinant tissue plasminogen activator (rtPA), administered intraperitoneally, reduces intra-abdominal abscess formation in rats with fecal peritonitis at the costs of increased mortality and early Escherichia coli bacteremia. It was determined whether or not mortality and bacteremia could be prevented by gentamycin in these rats. STUDY DESIGN Fecal peritonitis was induced by int...

Bacterial wilt disease caused by Ralstonia solanacearum (Smith) Yabuuchi is one of the most important bacterial diseases in world. This study aimed to test some chemical compounds such as bactericides that were applied control under artificial inoculation conditions and their effects on yield potatoes greenhouse conditions.In vitro, tested (Cefalexin, Gentamycin, Copper sulphate) inhibit growth...

The microbial growth analysis was done with the method of (Microgen) with the usage of both Resin and Thioglycolate to cover any unwanted effects from antibiotics that the patient may have taken before. The treatment started with the placement of an external shunt with injection of Gentamycin 10 mg with Amikacin 30 mg daily intrathecaly (although Gentamycin and Amikacin showed no effect on the ...

We share our experience of a 50-year-old controlled hypertensive woman who had routine cataract surgery in her left eye. She was given retrobulbar Xylocaine with adrenalin and postoperative gentamycin. She subsequently became blind in the operated eye after developing macular infarction by the first day post operative and optic atrophy by 2 months postoperative. This could have been caused by v...

Recent advances in regenerative medicines indicate that adult Mesenchymal Stromal Cells are promising candidates for cell-based therapies because of their large in vitro expansion potential. During this expansion one of the main questions is obtaining a perfect combination of antibiotics that can be used safely on cultures with minimum interference on cellular levels. Considering this basic nee...

The aim of the present study was to determine the antimicrobial resistance pattern of bacterial foodborne pathogens and to know the suitable antibiotic in controlling of foodborne pathogens. Escherichia coli, Salmonella typhimurium, Staphylococcus aureus, Bacillus cereus, Pseudomonas Sps were tested with twelve antibiotics by disc diffusion method. Among all antibiotic streptomycin, cefpodoxeme...

Motility of pathogenic T. pallidum was maintained in aerobic in vitro cultures for several weeks using a special medium. The latter consisted of McCoy's 5a medium supplemented with glutathione, sodium pyruvate, HEPES buffer, gentamycin (garamycin), and fetal calf serum. The virulence of the organisms was lost in 5 to 6 days. No multiplication of the organisms was observed. Four antibiotics (vio...

Aminoglycosides as modifying factors modulated the phenotypic manifestation of mitochondrial rRNA mutations and the incomplete penetrance of hearing loss. In this report, using cybrids harboring the m.1494C>T mutation, we showed that gentamycin aggravated mitochondrial dysfunction in a combination of the m.1494C>T mutation. The m.1494C>T mutation was responsible for the dramatic reduction in th...

In this study the enhancement effect of Sophora pachycarpa roots' acetone extract on the antibacterial activity of gentamycin was evaluated against Staphylococcus aureus. Disc diffusion and broth dilution methods were used to determine the antibacterial activity of gentamycin in the absence and presence of plant extract and its various fractions separated by TLC. A clinical isolate of S. aureus...