Fundoplication is a standard treatment for gastroesophageal reflux disease (GERD) in neurologically impaired children. However, it has a high recurrence rate due to wrap herniation and disruption resulting from the failure or enlargement of the esophageal hiatus suture site. In adult patients with GERD, reinforcement of the sutured esophageal hiatus with a mesh significantly reduces the recurre...

Methods Hospital casemix data published by the Ministry of Health, Labor and Welfare (DPC [Diagnosis Procedure Combination] survey data) is used to construct a database of acute-care hospitals. Hospitals are then geo-coded, using their addresses, to calculate drive-times to a geographic mesh. The resulting hospital-to-mesh drive-time table is used to analyze accessibility to services in each re...

rent paraesophageal hernia by means of laparoscopic hiatal reinforcement using a 12 ” 10−cm titanium−covered polypropy− lene mesh. He began to experience non− specific epigastric abdominal discomfort 10 months later. An upper endoscopy re− vealed the presence of mesh at the gas− troesophageal junction (l" Fig. 1), which was then removed endoscopically, using grasping forceps (l" Fig. 2). Since ...

BACKGROUND AND OBJECTIVES Rectal prolapse is often repaired laparoscopically, frequently with the use of reinforcement material. Both synthetic and biologically derived materials reduce recurrence rate compared to primary suture repair. Synthetic mesh introduces potential complications such as mesh erosion, fibrosis, and infection. Urinary bladder matrix (UBM) represents a biologically derived ...

Background and Objectives Laparoscopic paraesophageal hernia repair (LPEHR) is the new standard, but the use of mesh is still debated. Biologic mesh has shown great promise, but only the U-shaped onlay has been extensively studied. Postoperative dysphagia has historically been a concern with the use of synthetic keyhole mesh and subsequently slowed its adoption. The purpose of our study was to ...

BACKGROUND Abdominal closure in the presence of enterocutaneous fistula, stoma or infection can be challenging. A single-surgeon's experience of performing components separation abdominal reconstruction and reinforcement with mesh in the difficult abdomen is presented. METHODS Medical records from patients undergoing components separation and reinforcement with hernia mesh at Royal Liverpool ...

The paper focuses on the monitoring of an experimental stretch of road over a five year period in order to measure the effects of steel reinforcement on Asphalt Concrete (AC) pavement performance. The experimental stretch of road was constructed in 2001 alternating sections with and without steel reinforcement. This paper presents the results regarding the effects of steel reinforcement that we...

The use of high-throughput array and sequencing technologies has produced unprecedented amounts of gene expression data in central public depositories, including the Gene Expression Omnibus (GEO). The immense amount of expression data in GEO provides both vast research opportunities and data analysis challenges. Co-expression analysis of high-dimensional expression data has proven effective for...