OBJECTIVES To determine the risk of pelvic lymph node (LN) metastases at radical prostatectomy (RP) for Gleason score (GS) ≤7: 3 + 3 = 6 (grade group [GG]1); 3 + 4 = 7 (GG2); 3 + 4 = 7 (GG2) with tertiary pattern 5 (T5); 4 + 3 = 7 (GG3); 4 + 3 = 7 (GG3) with T5, using the 2014 modified Gleason grading system and the novel GG system. MATERIALS AND METHODS We searched our RP database to indenti...

We have developed a high-throughput, semiautomated, quantitative fluorescence-based PCR assay to detect and type herpes simplex virus (HSV) DNA in clinical samples. The detection assay, which uses primers to the type-common region of HSV glycoprotein B (gB), was linear from <10 to 10(8) copies of HSV DNA/20 microl of sample. Among duplicate samples in reproducibility runs, the assay showed less...

We propose a novel class of uniformly accurate integrators for the Klein--Gordon equation which capture classical $c=1$ as well highly oscillatory nonrelativistic regimes $c\gg1$ and, at same time, allow low regularity approximations. In particular, schemes converge with order $\tau$ and $\tau^2$, respectively, under lower assumptions than schemes, such splitting or exponential integrator metho...

In the classical theory of acoustic waves, Blackstock's model was proposed in 1963 to characterize propagation sound thermoviscous fluids. this paper, we investigate large-time asymptotic behaviors linear Cauchy problem for general (that is, without Becker's assumption on monatomic perfect gases). We derive first- and second-order profiles solution as $t\gg1$ by applying refined WKB analysis Fo...

We study the dynamics of periodically forced May--Leonard system. extend previous results on field, and we identify different dynamical regimes depending strength attraction $\delta$ network frequency $\omega$ periodic forcing. focus our attention in case $\delta\gg1$ $\omega \approx 0$, where show that, for a positive Lebesgue measure set parameters (amplitude forcing), are dominated by strang...

The evolution of many close binary and multiple star systems is defined by phases mass exchange interaction. As these evolve into contact, tidal dissipation not always sufficient to bring them circular, synchronous orbits. In cases, encounters increasing strength occur while the orbit remains eccentric. This paper focuses on outcomes passages in eccentric Close excite dynamical oscillations abo...

Primary bone lymphoma (PBL) is a rare disease for which specific therapeutic guidelines have not yet been established. Due to common appearance in the elderly and recurring relapses, new treatments are required. We report the case of multiple relapsed aggressive PBL effectively treated using Bendamustine and Rituximab. A 78-year-old male patient presented with a painful mass in the left arm. Co...

In this paper, we investigate the strong cosmic censorship conjecture (SCC) for charged black holes in de Sitter space by considering weak gravity (WGC). Using analytical methods, find that SCC is preserved dS-charged with respect to some restriction $qQ\gg1$ and $r_+\geq Q$ help of WGC condition viz $\frac{q}{m}\geq 1$ scalar fields. Where q, m are charge mass field, $r_+$, Q determine radius ...

We performed a serological evaluation of herpes simplex virus (HSV) infections at the time of labor. In order to determine the seroprevalence of asymptomatic HSV infections in pregnant women, blood samples were collected for antibody measurement from 130 randomly selected pregnant women. Presence of HSV IgG and IgM antibodies in the serum samples was tested by ELISA. The prevalence of HSV-1 gG1...