Phyllodes tumors are rare fibroepithelial neoplasms of the breast. In the literature, borderline or malignant tumors have been reported to present with unusual characteristics including a short clinical history and extremely rapid tumor growth. Skin necrosis and infection sometimes accompanies these malignancies. Giant phyllodes tumors have a good prognosis when treated with total mastectomy, b...

background: phyllodes tumors are uncommon neoplasms of the breast. data about their outcome is limited. this study aims to evaluate patients diagnosed with phyllodes tumors in terms of local recurrence, distant metastasis and overall survival. methods: we retrospectively reviewed the medical records of 129 women with phyllodes tumors who referred to our center from 1999 to 2013. clinical and pa...

OBJECTIVE Phyllodes tumor is a rare fibroepithelial neoplasia of the breast. Tumors are classified according to the histological criteria as benign, borderline, malignant groups. Criteria used to discriminate benign/malignant cases are stromal cytological atypia, stromal hypercellularity, mitotic rate, stromal overgrowth, and tumor margins. We designed this study retrospectively to see the vali...

Phyllodes tumor is an uncommon fibro epithelial breast tumor with diverse biological behavior. The tumor closely resemble as fibroadenoma of the breast. On one end phyllodes is slow growing benign tumor, the other end tumor grows rapidly behave like sarcoma which metastasizes, and phyllodes can turn to frank sarcoma. Tumor can be diagnosed on clinical basis i.e. large mass with lobulated (bosse...

background: phyllodes tumor (pt) of the breast in hispanic patients is more frequently reported with large tumors and with more borderline/malignant subtypes compared with other populations. the objective of this study was to describe characteristics of patients with pt and to identify differences among subtypes in a mexican population.  methods: a retrospective study was conducted on patients ...

Phyllodes tumour is an unusual fibroepithelial tumour of the breast constituting only 0.3% to 0.5% of all breast lesions.1,2 It usually occurs in middle-aged women. The median size of phyllodes tumour is 4 cm; however, 20% of these tumours grow larger than 10 cm and are known as giant phyllodes tumours. We report here a rare case of a middle-aged woman who presented to her family physician with...

Phyllodes tumors of breast, even histologically diagnosed as benign, can recur locally and have metastatic potential. Histologic markers only have limited value in predicting the clinical behavior of phyllodes tumors. It remains unknown what drives the malignant progression of phyllodes tumors. We found that the expression of myofibroblast markers, a-smooth muscle actin (a-SMA), fibroblast acti...

Phyllodes tumors of breast, even histologically diagnosed as benign, can recur locally and have metastatic potential. Histologic markers only have limited value in predicting the clinical behavior of phyllodes tumors. It remains unknown what drives the malignant progression of phyllodes tumors. We found that the expression of myofibroblast markers, α-smooth muscle actin (α-SMA), fibroblast acti...

Objective: The purpose of this study was to evaluate if MR imaging could differentiate phyllodes breast tumors and fibroadenomas. Materials and Methods: Dynamic contrast enhanced MR imaging was performed for six patients with six phyllodes breast tumors and results were compared with respect to morphology and contrast enhancement with those of 69 fibroadenomas of 50 patients. Results: Smooth ma...

Phyllodes tumors and fibroadenomas are the most common benign breast tumors. They arise from intralobular fibrous tissue as a unique lesion and after a period of time they differentiate in two direction: to fibroadenoma and to phyllodes tumors. Fibroadenomas grow up to 2-3 cm and then stop growing but phyllodes tumors grow continually and sometimes are to 40 cm big. Both these lesions have two ...